Dyspepsia and Peptic Ulcer disease Flashcards Preview

GastroIntestinal (GI) > Dyspepsia and Peptic Ulcer disease > Flashcards

Flashcards in Dyspepsia and Peptic Ulcer disease Deck (21):
1

What is dyspepsia?

Epigastric pain when full
(patients refer to indigestion)

2

What is function dyspepsia?

Dyspepsia for greater than 3 months

3

What are the causes of dyspepsia?

Functional dyspepsia/ Irritable bowl
Medication induced
GORD
Peptic ulcer disease
Gastric cancer

4

What is the universal investigation of dyspepsia?

Endoscopy

5

What are symptoms of severe dyspepsia?

Chronic gastrointestinal bleeding
Progressive unintentional
Weight Loss (Cachexia)
Dysphagia
Persistent vomiting
Iron deficiency anaemia
Epigastric mass or suspicious barium meal
Peritonism (Inflammation of the peritoneum)

6

What are medication causes of dyspepsia?

NSAID
Aspirin
Corticosteroids
Iron
Antibiotics
Calcium antagonists
Nitrates

7

What is is the management of dyspepsia?

Lifestyle advice
Antacids

8

What bacteria could cause dyspepsia?

H pylori

9

How is H pylori testing done?

Carbon 13 testing urea breath test
Stool antigen test
Serology

10

What antibiotics can be used against H Pylori?

Amoxocillin
Clarithromycin
Metrondiazole

11

What is the treatment for dyspepsia?

First line: Life style advice

If not responding : Proton Pump inhibitor ("prazole" )

If not responding: Prokinetics and H2 antagonist (Histamine antagonist)

12

What are pro kinetic treatments? Give an example of one.

Medications that control acid reflux and strengthen the lower oesophageal sphincter
e.g. metoclopramide, domperidone

13

What is the predominant cause of dyspepsia?

Functional dyspepsia (Irritable bowel)

14

If omeprazole has no effect, what should you do?

Prescribe Lansoprazole

15

What are the foregut structures?

Oesophagus
Stomach
Duodenum
Pancreas
Gallbladder

cricopharyngeus to ampulla of Vater

16

What is functional dyspepsia?

Dyspepsia with no evidence of culprit structural disease

17

What are the diagnostic criteria for function dyspepsia?

Postprandial Fullness (fullness with little intake of food)
Epigastric pain/ burning

18

What drugs are used in anti-secretory therapy?

PPI
H2 receptor antagonists

19

What are examples of H2 receptor antagonists?

Cimetidine
Ranitidine
Famotidine
Nizatidine

("tidines")

20

What are examples of PPI

"Prazoles"

21

Complications of Peptic ulcer disease?

Anaemia
Bleeding
Perforation
Fibrotic scaring -> obstruction