Flashcards in Viral Hepatitis Deck (13):
What are the hepatitis viruses?
How is Hepatitis A transmitted?
Faecal - oral spread
Men who have sex with men
What are the clinical signs of Hepatitis A ?
No chronic infection
short incubation time
How is Hepatitis A confirmed in the lab?
Clotted blood for serology
Hepatitis A test for IgM
How is Hepatitis E spread?
Faecal oral route - commonly found in the tropics
Found in under cooked pork / contact with pigs
How is Hepatitis D spread?
Can only get Hep D, if they already have an infection of B
- this is called superinfection
How is Hepatitis B transmitted?
Mother to child infection
Blood to blood contact
How is Hepatitis B detected in the lab?
Hepatitis B surface antigen
Hep B IgM likely to be present in recent infected cases
Long incubation times
Explain what you do if you have a patient with risk of having Hep C?
Test for Hep C antibody
Postive test; determine is past or active infection
Test for Hep C virus RNA by PCR
Position PCR: active infection
Explain what are the pathology of viral hepatitis ?
Acute Hepatitis / Acute liver failure
What is the management of chronic viral hepatitis?
Hepatocellular carcinoma awareness
What is the effect of an interferon alfa injection?
Inferferon alfa is a human protein, which can be given by injection as a pregylated interferon