Viral Hepatitis Flashcards Preview

GastroIntestinal (GI) > Viral Hepatitis > Flashcards

Flashcards in Viral Hepatitis Deck (13):
1

What are the hepatitis viruses?

Hepatitis A
Hepatitis B
Hepatitis C
Hepatitis D
Hepatitis E

2

How is Hepatitis A transmitted?

Faecal - oral spread
Poor hygiene
Overcrowding
Men who have sex with men

3

What are the clinical signs of Hepatitis A ?

Acute hepatitis
No chronic infection
short incubation time

4

How is Hepatitis A confirmed in the lab?

Clotted blood for serology
Hepatitis A test for IgM

5

How is Hepatitis E spread?

Faecal oral route - commonly found in the tropics
Found in under cooked pork / contact with pigs

6

How is Hepatitis D spread?

Can only get Hep D, if they already have an infection of B
- this is called superinfection

7

How is Hepatitis B transmitted?

Sexual intercourse
Mother to child infection
Blood to blood contact

8

How is Hepatitis B detected in the lab?

Hepatitis B surface antigen
(HBsAg)
Hep B IgM likely to be present in recent infected cases
Long incubation times

9

Explain what you do if you have a patient with risk of having Hep C?

Test for Hep C antibody

Postive test; determine is past or active infection

Test for Hep C virus RNA by PCR

Position PCR: active infection

10

Explain what are the pathology of viral hepatitis ?

Infection
Acute Hepatitis / Acute liver failure
Chronic infection
Chronic hepatitis
Cirrhosis
Cancer
Death

11

What is the management of chronic viral hepatitis?

Antivirals
Vaccinations
Infection control
Hepatocellular carcinoma awareness
Inferferon alfa

12

What is the effect of an interferon alfa injection?

Inferferon alfa is a human protein, which can be given by injection as a pregylated interferon

13

How is Hepatitis C spread?

Spread by blood, blood products, possibly sexually
Short incubation period
Often assymptomatic
Disease waxes and wanes
Tends to become chronic