Flashcards in Exam 1; Autonomic Drugs Deck (68)
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1
This nervous system has short preganglia and long postganglia which allow the activation of other systems
sympathetic
2
This nervous system originates in the CNS or sacral spinal roots and has long preganglionic and short postganglionic
parasympathetics
3
All preganglionic neurons use this as a neurotransmitter
ACh
4
sympathetic postganglionic neurons use this a a neurotransmitter
NE
5
parasympathetic postganglionic neuros use this as a neurotransmitter
ACh
6
What two effects does the sympathetic system have on the eye
far focus
contraction of radial muscle = pupil enlargement "mydnasis"
7
What three effects does the parasympathetic system have on the eye
contracts the circular sphincter for pupil constriction (myosis)
contraction of cilliary muscle for accommodation; close focus
increased tear production
8
What three effects does the sympathetic system have on the digestive system
decreased secretions
decreased gastric motility
decreased sphincter tone
9
What three effects does the parasympathetic system have on the digestive system
increased salivary and digestive secretions
increased motility
increased sphincter tone
10
What two effects does the sympathetic nervous system have on the heart
increased heart rate
increased contractile force
11
What two effects does the parasympathetic system have on the heart
decreased rate
decreased force of contraction
12
What two effects does the sympathetic nervous system have on the blood vessels
muscle vessels relax
skin and gut vessels contract
13
What effect does the parasympathetic system have on the blood vessels
relaxes most blood vessels
14
What effect does the sympathetic system have on the lung
relaxation of bronchial smooth muscle
15
What effect does the parasympathetic system have on the lungs
constricts bronchial smooth muscle
16
What two effects does the sympathetic system have on the reproductive system
relaxation of the bladder
ejaculation
17
What two effects does the parasympathetic system have on the reproductive system
contraction of the bladder
erection
18
What effect does the sympathetic system have on metabolism
increase in blood glucose
19
What type of receptor does ACh bind to
cholinergic
20
This type of neurotransmitter receptor activation leads to altered ion channels
nictonic receptors
21
This type of neurotransmitter receptor activation leads to altered metabolism
muscarinic
22
Niconitic receptors are used by what portions of the autonomic nervous system
preganglionic of both
23
Muscarinic receptors are used by what portions of the autonomic nervous system
postganglionic parasympathetic
24
Adrenergic receptors are used by what portions of the autonomic nervous system
postganglionic sympathetic
25
These act on ACh receptors
cholinergic agents
26
What is the effect of cholinergic agents
increase in parasympathetic activity
myosis, increased GI motility, increased sweat/tears/saliva, constriction of bronchial SM, decrease in HR and contraction
27
What is the mechanism of direct acting cholinergic agonists
bind and cause activation
28
These three drugs are muscarinic agonists
muscarine
pilocarpine
bethanechol
29
These two drugs are nicotinic agonists
nicotine
succinylcholine
30
