Exam 1; Autonomic Drugs Flashcards Preview

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Flashcards in Exam 1; Autonomic Drugs Deck (68)
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1

This nervous system has short preganglia and long postganglia which allow the activation of other systems

sympathetic

2

This nervous system originates in the CNS or sacral spinal roots and has long preganglionic and short postganglionic

parasympathetics

3

All preganglionic neurons use this as a neurotransmitter

ACh

4

sympathetic postganglionic neurons use this a a neurotransmitter

NE

5

parasympathetic postganglionic neuros use this as a neurotransmitter

ACh

6

What two effects does the sympathetic system have on the eye

far focus
contraction of radial muscle = pupil enlargement "mydnasis"

7

What three effects does the parasympathetic system have on the eye

contracts the circular sphincter for pupil constriction (myosis)
contraction of cilliary muscle for accommodation; close focus
increased tear production

8

What three effects does the sympathetic system have on the digestive system

decreased secretions
decreased gastric motility
decreased sphincter tone

9

What three effects does the parasympathetic system have on the digestive system

increased salivary and digestive secretions
increased motility
increased sphincter tone

10

What two effects does the sympathetic nervous system have on the heart

increased heart rate
increased contractile force

11

What two effects does the parasympathetic system have on the heart

decreased rate
decreased force of contraction

12

What two effects does the sympathetic nervous system have on the blood vessels

muscle vessels relax
skin and gut vessels contract

13

What effect does the parasympathetic system have on the blood vessels

relaxes most blood vessels

14

What effect does the sympathetic system have on the lung

relaxation of bronchial smooth muscle

15

What effect does the parasympathetic system have on the lungs

constricts bronchial smooth muscle

16

What two effects does the sympathetic system have on the reproductive system

relaxation of the bladder
ejaculation

17

What two effects does the parasympathetic system have on the reproductive system

contraction of the bladder
erection

18

What effect does the sympathetic system have on metabolism

increase in blood glucose

19

What type of receptor does ACh bind to

cholinergic

20

This type of neurotransmitter receptor activation leads to altered ion channels

nictonic receptors

21

This type of neurotransmitter receptor activation leads to altered metabolism

muscarinic

22

Niconitic receptors are used by what portions of the autonomic nervous system

preganglionic of both

23

Muscarinic receptors are used by what portions of the autonomic nervous system

postganglionic parasympathetic

24

Adrenergic receptors are used by what portions of the autonomic nervous system

postganglionic sympathetic

25

These act on ACh receptors

cholinergic agents

26

What is the effect of cholinergic agents

increase in parasympathetic activity
myosis, increased GI motility, increased sweat/tears/saliva, constriction of bronchial SM, decrease in HR and contraction

27

What is the mechanism of direct acting cholinergic agonists

bind and cause activation

28

These three drugs are muscarinic agonists

muscarine
pilocarpine
bethanechol

29

These two drugs are nicotinic agonists

nicotine
succinylcholine

30

This is a partial nicotinic agonist; binds, but does not fully activate; ACh cannot bind

varenicline