Exam 3; Cardiovascular Drugs Flashcards Preview

AU14 Pharmacology > Exam 3; Cardiovascular Drugs > Flashcards

Flashcards in Exam 3; Cardiovascular Drugs Deck (75)
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1

What is an arrhythmia

alternation in the normal impulse pathway

2

What can be two causes of an arrhythmia

alteration in the pacemaker
alteration in the transmission pathway

3

This is the source of the start of a rhythm

ectopic focus

4

Which is worse, ventricular or atrial fibrillation

ventricular; life threatening

5

What can result from ventricular fibrillation

decreased CO
clots may form

6

What is a major cause of sudden cardiac death

ventricular arrhythmias

7

Why is a non-drug treatment preferred for an arrhythmia

drug treatments may further cause arrhythmias

8

What are four types of non-drug treatments of arrhythmia

pacemaker implantation
cardioversion
automatic defibrillator implantation
surgical removal of an ectopic signal

9

This family of drugs are Na channel blockers that decrease the rate of depolarization

local anesthetics

10

This Na channel blocker can be used for all arrhythmias; depresses muscle function and anticholinergic effects

La-quinidine

11

What are three symptoms of La-quinidine

GI upset
vomiting
anorexia

12

What are two CNS effects of la-quinidine

tinnitus
altered color vision

13

This Na blocker does not enter the CNS, so no CNS effects and has a lupus like effect in low acetylators

procainamide

14

This Na channel blocker has strong anti-vagal effects; anti-muscarinic effects or oppostie of DUMBELLS

disopyramide

15

This Na channel blocker is give IV due to the first pass effect has low toxicity and is useful for treating ventricular tachycardia

Lb-lidocaine

16

What are two symptoms of lb-lidocaine

tremors and seizures

17

This Na channel blocker is given orally, has low toxicity and is useful for treating ventricular tachycardia; can result in tremors and seizures

mexiletine

18

What are the 5 Na channel blockers (anti-arrhythmia)

la-quinidine
procainamide
disophyamide
lb-lidocaine
mexiletine

19

These three drugs are anti-arrhythmia beta blockers

propranolol
metaprolol
esmolol

20

What is the mechanism behind the beta blockers

block the beta1 receptors in the heart
effectively slows the heart rate

21

This beta blocker decreases the pacemaker firing rate

propranolol

22

This beta blocker is more selective and has less beta 2 effects

metaprolol

23

This beta blocker has a more rapid onset

esmolol

24

What are three symptoms of beta blockers

bradycardia
hypotension
if there is a beta2 effect, asthma

25

What are the three potassium channel blockers

sotalol
amiodarone
dronedarone

26

This is a beta blocker that also blocks K channels

sotalol

27

This is a Na, K, and beta blockader

amiodarone

28

This is the most effective anti-arrhythmic; DOC in cases of cardiac arrest

amiodarone

29

This is an analog of amiodarone, with fewer side effects and less efficacy

dronedarone

30

This drug has symptoms such as potentially fatal pulmonary fibrosis, liver damage, blue-grey skin coloration, and GI upset

amiodarone