Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

AU14 Pharmacology > Exam 3; SE and Treatments > Flashcards

Exam 3; SE and Treatments Flashcards

(64 cards)

Start Studying
1
Q

SE: agranulocytosis

A

ticlopidine (ADP receptor blocker)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

SE: anorexia

A

quinidine (Na+ channel blocker)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

SE: anti-DUMBBELS (anti-muscarinic)

A

disopyramide (Na+ channel blocker)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

SE: anti-vagal effects (2)

A

quinidine, disopyramide (Na+ channel blockers)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

SE: asthma

A

“olol”s (Class II beta blockers)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

SE: bradycardia

A

“olol”s (Class II beta blockers)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

SE: bleeding/hemorrhage (3)

A

heparin (activates antithrombin)
warfarin (inhibits enzyme)
dabigatran (inhibits thrombin)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

SE: bleeding after spinal tap/surgery

A

rivaroxaban, apixaban (inhibits factor Xa)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

SE: intra-cranial bleeding

A

vorapaxar (thrombin receptor blocker)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

SE: prolong bleeding time

A 
thrombolytic agents (convert plasminogen --> plasmin)
ie streptokinase, urokinase, TPA
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

SE: toxic effects on conductive tissues

A

digoxin (inhibits Na-K-ATPase)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

SE: optic neuritic

A

amidorone (K+ channel blocker)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

SE: cutaneous flusing

A

niacin (inhibits enzyme, may bind a receptor –> block VLDL synthesis)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

SE: skin flushing

A

nitrates (activate guanylate cyclase enzyme)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

SE: diabetes

A

niacin (inhibits enzyme, may bind a receptor –> block VLDL synthesis)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

SE: inc uric acid –> gout

A

niacin (inhibits enzyme, may bind a receptor –> block VLDL synthesis)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

SE: hallucinations

A

digoxin (inhibits Na-K-ATPase)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

SE: HIT (loss of platelets)

A

heparin (activates antithrombin)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

SE: hypotension (2)

A

GTN (activate guanylate cyclase enzyme)

“olol”s (CLass II beta blockers)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

SE: itching

A

niacin (inhibits enzyme, may bind a receptor –> block VLDL synthesis)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

SE: iodine deposits

A

amidorone (K+ channel blocker)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

SE: liver damage (3)

A

amiodarone (K+ channel blocker - all four)
“statin”s (inhibit HMG-CoA reductase enzyme)
lomitapide (inhibits assembly of VLDL –> hepatotoxicity)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

SE: lupus-like syndrome

A

procainamide (Na+ channel blockers)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

SE: myocardial infarction

A

“afils” (inhibit Type 5 cGMP phosphodiesterase enzyme)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
SE: myositis --> rhabomyolsis
"statin"s (inhibit HMG-CoA reductase enzyme)
26
SE: severe nausea
digoxin (inhibits Na-K-ATPase)
27
SE: neural tube defects
folic acid deficiency during pregnancy
28
SE: neural damage (weakness, ataxia, spasticity, irreversible SC damage)
lack of methionine (due to vit B12 deficiency)
29
SE: neutropenia
ticlopidine (ADP receptor blocker)
30
SE: osteoporosis
herparin (activates anti-thrombin)
31
SE: pulmonary fibrosis
amiodarone (K+ channel blocker - all four)
32
SE: excess RBC (--> inc BP, clotting, MI, stroke)
drugs to treat chronic renal failure/chemotherapy (epoietin alfa, darbepoietin, peginesatide)
33
SE: retina damage (NAOIN)
"afil"s (inhibit Type 5 cGMP phosphodiesterase enzyme)
34
SE: severe joint pain
sickle cell anemia (treat with hydroxyurea)
35
SE: spinal hematoma (2)
enoxaparin, dalteparin (low MW heparins - more effect on Xa than thrombin)
36
SE: affects stools (3)
ezetimibe (blocks cholesterol absp from gut) orlistat (inhibits GI + pancreatic lipase enzyme) olestra (body cannot absorb oil)
37
SE: stroke (2)
"afil"s (inhibit Type 5 cGMP phosphodiesterase enzyme) | drugs to treat chronic renal failure/chemotherapy (epoietin alfa, darbepoietin, peginesatide)
38
SE: thrombocytopenia (2)
heparin (activates anti-thrombin) | abciximba, tirofiban, eptifibatide (fibrinogen receptor blockers)
39
SE: tinnitus
quinidine (Na+ channel blocker)
40
SE: tremors, seizures
lidocaine (Na+ channel blocker)
41
SE: altered color
quinidine (Na+ channel blocker)
42
SE: blue/green coloration
amiodarone (K+ channel blocker - all four)
43
SE: green/yellow tint
digoxin (inhibits Na-K-ATPase)
44
SE: impaired blue/green color discriminiation
"afil"s (inhibit Type 5 cGMP phosphodiesterase enzyme)
45
SE: disrupt warfarin plasma binding sites
fibrates (bind PPAR - activating receptor) | ie gemfibrozil, fenofibrate
46
Treats: cardiac arrest
amiodarone (K+ channel blocker - all four)
47
Treats: used during coronary operation to decrease white thrombi
abciximba, tirofiban, eptifibatide (fibrinogen receptor blockers) in combo with heparin
48
Treats: heart attack
``` thrombolytic agents (convert plasminogen --> plasmin) ie streptokinase, urokinase, TPA ```
49
Treats: heavy menstruation
``` hemostatic agents (inhibits plasminogen) ie aminocaproic acid, transexamic acid ```
50
Treats: hemophelia
``` hemostatic agents (inhibits plasminogen) ie aminocaproic acid, transexamic acid ```
51
Use these drugs in place of heparin if HIT develops
hirudin (inhibits thrombin enzyme) | bivalirudin, desirudin, agratroban
52
Treats: pulmonary hypertension
"afil"s (inhibit Type 5 cGMP phosphodiesterase enzyme)
53
Treats: atrial tachycardia
adenosine (binds adenosine receptor --> dec AV firing node rate)
54
Treats: ventricular tachycardia
lidocaine (Na+ channel blocker)
55
Treats: micocytic anemia
iron (FeSO4), iron dextran
56
Treats: macrocytic anemia
folic acid
57
Treats: pernicious anemia
B12 injection
58
Treats: anemia due to chronic renal failure/chemotherapy
epoietin alfa, darbepoietin, peginesatide
59
Treats: sickle cell anemia
hydroxyurea
60
1st pass metabolism
lidocaine, GTN
61
enhance effects in hypokalemia
digoxin
62
P450
"afil"s warfarin "statin"s
63
can cross placenta
fondaparinux warfarin (FDA Cat X) hydroxyurea (FDA Cat D) "statin"s (FDA Cat X)
64
SE: dec absorption of fat soluble vitamins
cholestyramine, coleselevam, colestipol (bile acid binding proteins)

AU14 Pharmacology (29 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions