Lymphatic System Part II

Question 1

Molecule that is recognized by cells of adaptive immune system

Answer 1

ANTIGENS

Question 2

elicits a response from these cells

Answer 2

ANTIGENS

Question 3

Soluble molecules (proteins or polysaccharides)

Answer 3

ANTIGENS

Question 4

Proteins from the intact cell (bacteria, protozoa, or tumor cells)

Answer 4

ANTIGENS

Question 5

small molecular domains of the antigen

Answer 5

ANTIGENIC DETERMINANTS / EPIPTODES

Question 6

IMMUNE RESPONSE TO ANTIGENS:

Answer 6

a. Cellular
b. Humoral
c. both

Question 7

IMMUNE RESPONSE TO ANTIGENS:

in which lymphocytes are primarily in charge of eliminating the antigen.

Answer 7

Cellular

Question 8

IMMUNE RESPONSE TO ANTIGENS:

in which antibodies are primarily responsible for the response

Answer 8

Humoral

Question 9

a glycoprotein of the immunoglobulin family

Answer 9

ANTIBODIES

Question 10

interacts specifically with an antigenic determinant

Answer 10

ANTIBODIES

Question 11

isolated carboxyl-terminal portion of the heavy-chain molecules

Answer 11

FC REGION

Question 12

CLASSES OF ANTIBODIES:

Answer 12

I. IgG ANTIBODY
II. IgA ANTIBODY
III. IgM ANTIBODY
IV. IgE ANTIBODY
V. IgD ANTIBODY

Question 13

CLASSES OF ANTIBODIES:

Most abundant 75-85% in blood

Answer 13

IgG ANTIBODY

Question 14

CLASSES OF ANTIBODIES:

Increased during infections

Answer 14

IgG ANTIBODY

Question 15

CLASSES OF ANTIBODIES:

Highly soluble and stable (half-life> 3 weeks)

Answer 15

IgG ANTIBODY

Question 16

CLASSES OF ANTIBODIES:

Crosses placental barrier into the fetal circulation

Answer 16

IgG ANTIBODY

Question 17

CLASSES OF ANTIBODIES:

PASSIVE immunity against certain infections until the newborn’s own adaptive immunity is acquired

Answer 17

IgG ANTIBODY

Question 18

CLASSES OF ANTIBODIES:

Present in almost all exocrine secretions

Answer 18

IgA ANTIBODY

Question 19

CLASSES OF ANTIBODIES:

Dimeric form

Answer 19

IgA ANTIBODY

Question 20

CLASSES OF ANTIBODIES:

Heavy chains of two monomer are united by polypeptide J chain.

Answer 20

IgA ANTIBODY

Question 21

CLASSES OF ANTIBODIES:

Produced by plasma cells in mucosae of the digestive, respiratory, and reproductive tracts

Answer 21

IgA ANTIBODY

Question 22

CLASSES OF ANTIBODIES:

Secretory component – protects the antibody from proteolysis

Answer 22

IgA ANTIBODY

Question 23

CLASSES OF ANTIBODIES:

5-10%

Answer 23

IgM ANTIBODY

Question 24

CLASSES OF ANTIBODIES:

Pentameric form united by J chain

Answer 24

IgM ANTIBODY

Question 25

CLASSES OF ANTIBODIES: Produced in an initial response to an antigen

Answer 25

IgM ANTIBODY

Question 26

CLASSES OF ANTIBODIES: Most effective antibody class in activating complement system

Answer 26

IgM ANTIBODY

Question 27

CLASSES OF ANTIBODIES: less abundant in circulation

Answer 27

IgE ANTIBODY

Question 28

CLASSES OF ANTIBODIES: Found on the surface of the mast cells and basophils

Answer 28

IgE ANTIBODY

Question 29

CLASSES OF ANTIBODIES: Found on the surface of the mast cells and basophils

Answer 29

IgE ANTIBODY

Question 30

CLASSES OF ANTIBODIES: Triggers the release of histamine, heparin, and leukotrienes

Answer 30

IgE ANTIBODY

Question 31

CLASSES OF ANTIBODIES: Allergic reaction (allergens)

Answer 31

Allergic reaction (allergens)

Question 32

CLASSES OF ANTIBODIES: least abundant in plasma

Answer 32

IgD ANTIBODY

Question 33

CLASSES OF ANTIBODIES: least understood class of antibody

Answer 33

IgD ANTIBODY

Question 34

CLASSES OF ANTIBODIES: bound to the surface of B lymphocytes

Answer 34

IgD ANTIBODY

Question 35

CLASSES OF ANTIBODIES: act as antigen receptors in triggering B-cell activation.

Answer 35

IgD ANTIBODY

Question 36

Antigen-binding sites of IgG and IgA antibodies are able to:

Answer 36

bind specifically neutralize certain viral particles and bacterial toxins agglutinate many bacterial cells precipitate most soluble antigens

Question 37

precipitate most soluble antigens

Answer 37

Complement protein

Question 38

Will be activated through a cascade of enzymatic reactions

Answer 38

COMPLEMENT ACTIVATION

Question 39

specific complement components bind and rupture membranes of invading cell

Answer 39

After Complement Activation

Question 40

Clump antigen-bearing bacteria or cells

Answer 40

After complement activation

Question 41

Elicit arrival of relevant leukocytes

Answer 41

After complement activation

Question 42

Refers to the ability of receptors on macrophages, neutrophils, and eosinophils to recognize and bind the Fc portions of antibodies attached to surface antigens of microorganisms

Answer 42

OPSONIZATION

Question 43

Antibodies bound to antigens on virus-infected cells of the body are recognized by the primitive lymphocytes called ___

Answer 43

NK cells

Question 44

NK cells activation is Activated to kill the infected cell by releasing

Answer 44

perforin and various granzymes

Question 45

CELLS OF ADAPTIVE IMMUNITY

Answer 45

ANTIGEN-PRESENTING CELLS LYMPHOCYTES T LYMPHOCYTES B LYMPHOCYTES

Question 46

Active endocytotic systems

Answer 46

ANTIGEN-PRESENTING CELLS

Question 47

Mediate the cellular immune response by processing and present the antigens for recognition by certain lymphocytes

Answer 47

ANTIGEN-PRESENTING CELLS

Question 48

ANTIGEN-PRESENTING CELLS:

Answer 48

ANTIGEN-PRESENTING CELLS