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Histology > Lymphatic System Part II > Flashcards

Lymphatic System Part II Flashcards

(48 cards)

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1
Q

Molecule that is recognized by cells of adaptive immune system

A

ANTIGENS

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2
Q

elicits a response from these cells

A

ANTIGENS

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3
Q

Soluble molecules (proteins or polysaccharides)

A

ANTIGENS

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4
Q

Proteins from the intact cell (bacteria, protozoa, or tumor cells)

A

ANTIGENS

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5
Q

small molecular domains of the antigen

A

ANTIGENIC DETERMINANTS / EPIPTODES

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6
Q

IMMUNE RESPONSE TO ANTIGENS:

A

a. Cellular
b. Humoral
c. both

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7
Q

IMMUNE RESPONSE TO ANTIGENS:

in which lymphocytes are primarily in charge of eliminating the antigen.

A

Cellular

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8
Q

IMMUNE RESPONSE TO ANTIGENS:

in which antibodies are primarily responsible for the response

A

Humoral

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9
Q

a glycoprotein of the immunoglobulin family

A

ANTIBODIES

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10
Q

interacts specifically with an antigenic determinant

A

ANTIBODIES

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11
Q

isolated carboxyl-terminal portion of the heavy-chain molecules

A

FC REGION

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12
Q

CLASSES OF ANTIBODIES:

A

I. IgG ANTIBODY
II. IgA ANTIBODY
III. IgM ANTIBODY
IV. IgE ANTIBODY
V. IgD ANTIBODY

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13
Q

CLASSES OF ANTIBODIES:

Most abundant 75-85% in blood

A

IgG ANTIBODY

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14
Q

CLASSES OF ANTIBODIES:

Increased during infections

A

IgG ANTIBODY

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15
Q

CLASSES OF ANTIBODIES:

Highly soluble and stable (half-life> 3 weeks)

A

IgG ANTIBODY

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16
Q

CLASSES OF ANTIBODIES:

Crosses placental barrier into the fetal circulation

A

IgG ANTIBODY

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17
Q

CLASSES OF ANTIBODIES:

PASSIVE immunity against certain infections until the newborn’s own adaptive immunity is acquired

A

IgG ANTIBODY

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18
Q

CLASSES OF ANTIBODIES:

Present in almost all exocrine secretions

A

IgA ANTIBODY

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19
Q

CLASSES OF ANTIBODIES:

Dimeric form

A

IgA ANTIBODY

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20
Q

CLASSES OF ANTIBODIES:

Heavy chains of two monomer are united by polypeptide J chain.

21
Q

CLASSES OF ANTIBODIES:

Produced by plasma cells in mucosae of the digestive, respiratory, and reproductive tracts

22
Q

CLASSES OF ANTIBODIES:

Secretory component – protects the antibody from proteolysis

23
Q

CLASSES OF ANTIBODIES:

5-10%

24
Q

CLASSES OF ANTIBODIES:

Pentameric form united by J chain

25
CLASSES OF ANTIBODIES: Produced in an initial response to an antigen
IgM ANTIBODY
26
CLASSES OF ANTIBODIES: Most effective antibody class in activating complement system
IgM ANTIBODY
27
CLASSES OF ANTIBODIES: less abundant in circulation
IgE ANTIBODY
28
CLASSES OF ANTIBODIES: Found on the surface of the mast cells and basophils
IgE ANTIBODY
29
CLASSES OF ANTIBODIES: Found on the surface of the mast cells and basophils
IgE ANTIBODY
30
CLASSES OF ANTIBODIES: Triggers the release of histamine, heparin, and leukotrienes
IgE ANTIBODY
31
CLASSES OF ANTIBODIES: Allergic reaction (allergens)
Allergic reaction (allergens)
32
CLASSES OF ANTIBODIES: least abundant in plasma
IgD ANTIBODY
33
CLASSES OF ANTIBODIES: least understood class of antibody
IgD ANTIBODY
34
CLASSES OF ANTIBODIES: bound to the surface of B lymphocytes
IgD ANTIBODY
35
CLASSES OF ANTIBODIES: act as antigen receptors in triggering B-cell activation.
IgD ANTIBODY
36
Antigen-binding sites of IgG and IgA antibodies are able to:
bind specifically neutralize certain viral particles and bacterial toxins agglutinate many bacterial cells precipitate most soluble antigens
37
precipitate most soluble antigens
Complement protein
38
Will be activated through a cascade of enzymatic reactions
COMPLEMENT ACTIVATION
39
specific complement components bind and rupture membranes of invading cell
After Complement Activation
40
Clump antigen-bearing bacteria or cells
After complement activation
41
Elicit arrival of relevant leukocytes
After complement activation
42
Refers to the ability of receptors on macrophages, neutrophils, and eosinophils to recognize and bind the Fc portions of antibodies attached to surface antigens of microorganisms
OPSONIZATION
43
Antibodies bound to antigens on virus-infected cells of the body are recognized by the primitive lymphocytes called ___
NK cells
44
NK cells activation is Activated to kill the infected cell by releasing
perforin and various granzymes
45
CELLS OF ADAPTIVE IMMUNITY
ANTIGEN-PRESENTING CELLS LYMPHOCYTES T LYMPHOCYTES B LYMPHOCYTES
46
Active endocytotic systems
ANTIGEN-PRESENTING CELLS
47
Mediate the cellular immune response by processing and present the antigens for recognition by certain lymphocytes
ANTIGEN-PRESENTING CELLS
48
ANTIGEN-PRESENTING CELLS:
ANTIGEN-PRESENTING CELLS

Histology (37 decks)

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