Mesothelioma Flashcards

(9 cards)

1
Q

What type of cancer is mesothelioma?

A

Cancer of mesothelial cells

Mesothelial cells line the pleura, peritoneum, and pericardium.

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2
Q

What is the primary cause of mesothelioma?

A

Prior occupational exposure to asbestos

Patients with a history of working with asbestos are at higher risk.

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3
Q

What condition typically occurs before mesothelioma?

A

Asbestosis

Asbestosis is a chronic lung disease caused by asbestos exposure.

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4
Q

Who are commonly affected by mesothelioma due to occupational exposure?

A

Shipyard and construction workers

These professions involve significant asbestos exposure.

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5
Q

chest X-ray for asbestosis?

A

Asbestosis will be described as pleural or supradiaphragmatic plaques (“soft tissue plaques seen on CXR”).

CXR stands for chest X-ray.

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6
Q

What does a pulmonary biopsy show in cases of asbestosis?

A

Ferruginous bodies

Ferruginous bodies are asbestos fibers coated with iron.

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7
Q

What protein is highly indicative of mesothelioma on staining?

A

Calretinin

Calretinin is a marker used in immunohistochemistry.

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8
Q

How is mesothelioma typically described in terms of its appearance?

A

Mesothelioma appears as a whiteish cancer and is described as an “encasing rind
of pleural-based tumor” (i.e., circumferentially surrounds/wraps around the lungs).

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9
Q
A

Mesothelioma

Mesothelioma appears as a whiteish cancer and is described as an “encasing rind
of pleural-based tumor” (i.e., circumferentially surrounds/wraps around the lungs).

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