Reactive arthritis

Question 1

What is the classic triad presentation of reactive arthritis?

Answer 1

1) Urethritis or abdominal infection, 2) Polyarthritis, 3) Eye-itis (conjunctivitis, episcleritis, or anterior uveitis)

The term ‘eye-itis’ refers to inflammation of the eye, which can manifest in various forms such as conjunctivitis, episcleritis, or anterior uveitis.

Question 2

Which organism is classically associated with reactive arthritis?

Answer 2

Chlamydia

Gonococcus is not associated with reactive arthritis on the USMLE.

Question 3

Name three other infections that can cause reactive arthritis besides Chlamydia.

Answer 3

• Rubella
• Hepatitis B and C
• Yersinia

These infections can lead to reactive arthritis, although Chlamydia is the most classic causative agent.

Question 4

Reactive arthritis is part of which constellation?

Answer 4

HLA B27 PAIR

PAIR stands for Psoriatic arthritis, Ankylosing spondylitis, Inflammatory bowel disease, and Reactive arthritis.