Uticarial Transfusion Reaction

Question 1

Urticarial transfusion reaction cause

Answer 1

Preformed IgE antibodies in recipient reacting with allergens in donor plasma (or vice versa)

Question 2

Urticarial transfusion reaction presentation and mangement

Answer 2

Isolated Urticaria that improve with transfusion cessation and diphenhydramine

If no signs of anaphylaxis are present (angioedema, wheezing, hypotension), transfusion can be continued with no further evaluation