Limbic System Lec16 Flashcards

(66 cards)

1
Q

parts of the papez circuit actually involved in emotions

A

cingulate cortex and the hypothalamus

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2
Q

Areas of the limbic system involved in emotional processing

A

amygdala, anterior and mid-cingulate cortex, mediodorsal nucleus of the thalamus and prefrontal cortex.

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3
Q

Primary emotions are reflexive and involve the (3)

A

amygdala, hypothalamus, and PAG

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4
Q

what primarily drives primary emotions?

A

the amygdala —- which gets input from the auditory pathway (or visual) via the thalamus as well as directly from the auditory pathway.

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5
Q

___ emotions are conscious

A

Secondary

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6
Q

secondary emotions and involve the ___

A

cortical limbic structures

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7
Q

Stimulation of the___ with norepinephrine induces the fight or flight response

A

dorsolateral portion of the PAG

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8
Q

. Stimulation of the ___ portion of PAG with norepinephrine leads to hypoactivity

A

ventral

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9
Q

Since the ___ nuclei project to the PAG, you can also stimulate the ___ nuclei for the same effect.

A

hypothalamic

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10
Q

You need the ___ and ___ to regulate emotions.

If you get a stroke or tumor to either one of these regions you lose control of your emotions and can result in sham rage (excessive rage without external control)

A

hypothalamus or the PAG

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11
Q

. Only th___ and ___ cingulate cortex play a role in emotional processing.

A

cingulate cortex

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12
Q

is the posterior cingualte cortex ivnovled in emotion?

A

no

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13
Q

. It may be useful to think of serotonin as mood ___

A

altering

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14
Q

. It may be useful to think of norepinpehrine as mood

A

elevating

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15
Q

what is included in the papez circuit

A
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16
Q

___ is the synapse site of the limbic system in the thalamus

A

mediodorsal n.

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17
Q

primary emotions are linked with ___ reflexes

A

autonomic

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18
Q

If a monkey’s temporal lobe / amygdala was removed, the animal became (4)

A
  1. docile
  2. hyperoral
  3. hypersexual
  4. and ate inappropriate items.
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19
Q

Urbach-Wiethe disease = what is the cause and what are the sx?

A

calcification & loss of amygdala

  1. no fear response
  2. can’t recognize fear in faces
  3. risky behaviors
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20
Q

Fear response involves direct connections from

A

thalamus to amygdala

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21
Q

Shown by auditory-foot shock conditioning experiment. Even if amygdala/
auditory cortex connection was cut,

A

fear was still present

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22
Q

Amygdala connects to __ and __ for fight-or-flight response

A

PAG and LC

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23
Q

Stimulation of ___ PAG = fight-or-flight,

A

Dorsal

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24
Q

lesion of Dorsal PAG

A

affective defense & “sham rage”

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25
lesion fo ventral pag
quiet, biting
26
All major emotion structures are connected to the \_\_
PAG
27
The PAG regulates ANS via
soliary n. dorsal mtoor fo vagus IML
28
The hypothalamus-pituitary axis (HPA) is driven by the (3)
amygdala, limbic cortex, & locus coeruleus
29
Amygdala / Insula / Limbic Cortex (ACC) --\> Paraventricular Nucleus (PVN) of hypothalamus --\>
CRH
30
the amygdala projects to which cingulate cortex?
the ACC and anterior MCC
31
the ___ region of the cingulate cortex (around the genu of the corpus callosum) is extra vulnerable to emotional diseases like depression
perigenual
32
anterior cingulate cortex connects the ans to the
solitary n. and dosal mtoor of vagus
33
emotion associated with ventral acc
sadness
34
emotion associated with rostral acc
hapiness
35
"Facial Region" of the ACC is impacted by what emotions
all of them
36
emotiona ssociated witht the **anterior mid cingualte cortex**
fear
37
Electrical stimulation of the MCC evokes complex motor responses like (3)
lip puckering, finger kneading, and bilateral limb movements
38
fear response input goes directlyfrom the thalamus to the
amygdala --\> fear response
39
fear response ## Footnote thalamus -\> amygdala --\>
ACC (upstream) and the PAG and LC (downstream pathways)
40
thalamus --\> amygdala --\> ACC (upstream) and the PAG (downstream pathways) --\> both faical. n and facial expression activated so fear is expressed ___ and \_\_
somatically and viscerally
41
fear response Memory of event is encoded in the\_\_ and \_\_
amygdala and cortex
42
fear response memory of event is enhanced by
norepinpehrine
43
locus coerelus regulates the
hpa axis
44
Locus Coeruleus is connected to...
solitary ncuelus pag pvn of hypothalamus amygdala and limbic paraventricular nucleus of the thalamus
45
Locus Coeruleus --\> solitary n. --\>
visceral motor center for heart rate
46
LC --\> pag --\>
fight to flight
47
\_\_\_\_ drives PVN/HPA axis
LC/NE
48
LC --\> Amygdala & Limbic Cortex (cingulate, insular, orbitofrontal) --\>
enhance emotional memory formation
49
The Raphe Nuclei project from midbrain to \_\_\_
forebrain
50
\_\_\_ disfunction leads to conduct disorders, criminal psychopathy, other sociopathies, PTSD
Limbic system
51
In patients with severe depression, ___ shows decreased glucose metabolism / reduced activity
anterior cingulate cortex
52
Risk factor for depression: No ____ control of amygdala = increased fear and anxiety.
anterior cingulate control
53
SSRIS bind strongly to the
anterior cingulate cortex
54
deep brain stimulation can create substantial improvement in people with intractable depression if electrodes are placed near the
acc and amygdala
55
\_\_\_ is involved in AFFECT
Anterior cingulate cortex
56
\_\_\_ cortex is involved in motivated behavior and response selection
Midcingulate
57
\_\_\_\_ has extensive projections to the striatum, red nucleus, pontine nuclei (cerebellum), and cranial nerve motor nuclei for somatomotor driving of alpha motor neurons.
midcingualte cortex
58
a very impotant connection in pyshiatry the amygdala has reciprocal projections to the
acc
59
PET studies show activation in ___ when remembering sad events.
ACC
60
Electrical simulation of the _____ produces complex motor outputs (that can be modified by context)
MCC
61
faical region in the acc projects to the
facial motor n. and the muscles of facial expression
62
facial region in the ___ of the cingualte cortex
acc
63
what do the reciptocal connections between the LC and the 1. amygadla and 2. cingulate cortex do?
involved in consolidation of emotional memories
64
storage of emotionall vlanece memories in the amygdala and acc depends on \_\_\_
norepineprine release by LC
65
how does locus corelus intercedes in limbic systems to coordinate motor outputs.
66
what structures are in the limbic lobe? (3)
cingulate cortex parahippocampal gyri olfactoruy cortex