NURSING II: MEDS - PART C Flashcards
Drugs used to treat gastric acid / acid neutralizers:
- Antacids
2. Acid-reducing agents
Drugs that affect UGI System (5):
- Antacids
- Acid-reducing agents
- Gastrointestinal Stimulants
- Antiemetics
- Emetics
Antacids: Action (2)
NEUTRALIZE or REDUCE acidity of the stomach -
- Combines with HCl
- Increases pH of the stomach acid
Antacids: Uses
- Heartburn, acid indigestion, sour stomach
- GERD
- Peptic Ulcer
Acid-reducing agents (2):
- Histamine 2 Antagonists
2. Proton Pump Inhibitors
Histamine 2 Antagonists: Action
Inhibits action of histamine -
reduces acid secretion by the stomach
Histamine 2 Antagonists: Uses (4)
- Heartburn, acid indigestion, sour stomach
- GERD
- Gastric and Duodenal Ulcer
- Gastric hypersecretory conditions
Proton Pump Inhibitors: Action
Antisecretory -
Inhibits ATP system, blocks final step in acid production
Antacids: Examples (3)
Tums
Mylanta
Milk of Magnesia
Acid Neutralizers: Administration
- Don’t take other drugs within 2 hours
2. Take 1-2 hrs after meals, and bedtime
Acid Neutralizers: Assessments (2)
- Pain, heartburn
2. Monitor IV rate of infusion
Acid Neutralizers: Too rapid of IV infusion may induce __ __.
cardiac arrhythmias.
Antacids may cause ___ stools.
chalky-white
Overuse of Acid Neutralizers may lead to the stomach ______.
secreting too much acid.
Gastrointestinal Stimulants: Action
Increases peristalsis
Gastrointestinal Stimulants: Uses
- GERD, gastric stasis (+ post-op)
2. Risk of paralytic ileus (given IV, Dexpanthenol)
Histamine 2 Antagonists: Examples
Pepcid
Zantac
Proton Pump Inhibitors: Examples
Nexium
Prilosec
Acid Neutralizers: Adverse Reactions
- Diarrhea
- Constipation
- Chalky, white, streaky stools
- CNS: nausea, drowsiness, headache, dizziness
Gastrointestinal Stimulants: Examples
Reglan
Hopan
Gastrointestinal Stimulants: Adverse Effects
- CNS: drowsiness, dizziness
2. Signs of Parkinson’s: extrapyramidal effects, repetitive/involuntary movements
Gastrointestinal Stimulants: Administration
First-choice for post-op
Gastrointestinal Stimulants: Assessments
- Bowel sounds
2. Nausea, vomiting
Gastrointestinal Stimulants: Teaching
Report any adverse reactions:
difficulty speaking, tremors, uncontrolled movements…
Antiemetics: Action
Inhibits CTZ (area of brain that triggers nausea, vomiting)
Antiemetics: Uses
Nausea, vomiting
Motion sickness
Vertigo
Antiemetics: Examples
- Phenergan
2. Compazine
Antiemetics: Adverse Reactions
CNS depression (drowsiness)
Antiemetics: Assessments
- Nausea, vomiting pattern
- Emesis contents
- Pain
- Hydration status
- Monitor LOC
Antiemetics: Administration
- before chemo, surgery
2. per rectal, IV, or transdermal patch
Antiemetics: Teaching
- Avoid hazardous tasks (CNS depression)
Emetics: Action
Stimulates CTZ
Emetics: Uses
Induce vomiting (poison, overdose)
Emetics: Example
Ipecac syrup