Prototype Drug Unit 5 & 7- Penicillin G (All your -cillins)

Question 1

Therapeutic effects and uses

Answer 1

used for pretty much every infection including Staph, Strep, Neisseria, Actinomyces, Bacillus anthracis, Clostridium, Treponema, and Corynebacterium.

Question 2

Therapeutic classification

Answer 2

Antibacterial

Question 3

Pharmacologic classification

Answer 3

Cell wall inhibitor, natural penicillin

Question 4

Mechanism of action

Answer 4

Inhibits bacterial wall synthesis by binding PBPs.

Question 5

Adverse effects

Answer 5

Rash, pruritus (severe itching of the skin), diarrhea, nausea, and fever

Question 6

Contraindications/precautions

Answer 6

Allergic to penicillin or any drug in the penicillin class.

Question 7

Drug interactions

Answer 7

Don’t take with oral contraceptives, colestipol, probenecid, potassium-sparing diuretics, aminoglycoside antibiotcs, and tetracyclines