Prototype Drug Unit 5 & 7- Chloroquine

Question 1

Therapeutic classification

Answer 1

Antimalarial drug

Question 2

Pharmacologic classification

Answer 2

Heme complexing agent

Question 3

Therapeutic effects and uses

Answer 3

Used mostly for the treatment of malaria

Question 4

Mechanism of action

Answer 4

Cuts off the food vacuole of the red blood cells in humans and prevents the parasite from eating from them. The parasite instead eats the drug and it builds to toxic levels in the parasite

Question 5

Adverse effects

Answer 5

Nausea, vomiting, diarrhea, visual changes, including blurred vision, photophobia, difficulty focusing

Question 6

Contraindications

Answer 6

Hypersensitivity, Retina probs, Porphyria, liver impairment, and kidney impairment

Question 7

Drug interactions

Answer 7

Antacids and laxatives containing aluminum and magnesium. Cimetidine, rabies vaccine, antidysrhythmics, phenothiazines, and beta-adrenergic agonists