A&P Chapter 12 Flashcards
What makes up the CNS?
Brain and spinal cord
What is cephalization?
Elaboration of the rostral or anterior portion of the CNS, an increase in the number of neurons in the head
What is the neural tube?
The brain and spinal cord begin as this embryonic structure
What is rostral?
Anterior
What is caudal?
Posterior
How does the neural tube compartmentalize?
The rostral end expands and constrictions appear that mark off three primary brain vesicles
What are the three primary brain vesicles that result from the neural tube?
- Forebrain - prosencephalon
- Midbrain - mesencephalon
- Hindbrain - rhombencephalon
What does the caudal portion of the neural tube become?
Develops into the spinal cord
What are the secondary brain vesicles of the forebrain (prosencephalon)?
Telencephalon - endbrain
Diencephalon - interbrain
What are the secondary brain vesicles of the hindbrain (mesencephalon)?
Metencephalon - afterbrain
Myelencephalon - spinal brain
What are the secondary brain vesicles of the midbrain (rhombencephalon)?
The midbrain does not divide
What happens once the primary brain vesicles form?
They rapidly develop to produce the major structures of the adult brain
Where does the greatest development occur?
The greatest change occurs in the telencephalon which sprouts two mickey mouse ears resulting the the two cerebral hemispheres
What does the diencephalon develop into?
Thalamus, hypothalamus, epithalamus, and retina
What does the mesencephalon develop into?
Midbrain
What does the metencephalon develop into?
Pons and cerebellum
What does the myelencephalon develop into?
Medulla
What does the central cavity of the neural tube develop into?
It enlarges in four areas to form the fluid filled ventricles
Why does the brain fold?
Because the brain grows faster than the skull so it folds to occupy more space
What vesicle arises from the telencephalon?
Lateral
What vesicle arises from the diencephalon?
Third
What vesicle arises from the mesencephalon?
Cerebral aqueduct
What vesicle arises from the metencephalon and myelencephalon?
Fourth
What do the convolutions of the brain do?
The increase the surface area and allow more neurons to occupy a limited space
What are the four major regions of the adult brain?
- Cerebrum
- Cerebellum
- Brain stem
- Diencephalon
Where are the gray and white matter in the brain?
Gray matter - cortex on the outer periphery
White matter - inside
What is found in gray matter?
Cell bodies and dendrites
What is found in white matter?
Myelinated axons
What is the outer layer of the cerebrum and cerebellum of gray matter?
Cortex
What are the ventricles filled with? What are the ventricles lined with?
Cerebrospinal fluid, ependymal cells
What structure separated the lateral ventricles?
Septum pellucidum
How does the pair of lateral ventricles communicate with the third ventricle?
The interventricular foramen, or foramen of Monroe
What is the third ventricle located above? What is the third ventricle located between?
Above the hypothalamus, between the thalamic nuclei
How does the third ventricle communicate with the fourth?
Cerebral aqueduct, or the aqueduct of Sylvius
What are the three openings of the fourth ventricle?
Lateral apertures (2) Median aperture
What is the other name for the lateral apertures of the fourth ventricle? Where are they located?
The foramen of Magendie, located on the side walls of the fourth ventricle
What is the other name for the median aperture of the fourth ventricle? Where is it located?
Foramen of Luschka, located on the roof of the fourth ventricle
Where does the fourth ventricle lie?
Between the brainstem and the cerebellum
Where does CSF travel through the spinal cord?
The central canal
What structure reabsorbs CSF back into the blood stream?
Arachnoid villa
What does the arachnoid villa look like?
Fingerlike extensions that project into the venous sinuses of the dura
Where is CSF produced?
The choroid plexuses
Where are choroid plexuses found?
In the superior portion of ventricles
What are the functions of CSF?
- Mechanical/chemical protection
2. Circulation - exchange of nutrients and waste products
What elements are including in CSF analysis?
- Opening pressure
- Color
- Cell count and differential
- Gram stain
- Culture
- Protein level
- Glucose level
What color is normal CSF? What color is abnormal?
Normal - clear
Abnormal - yellow, orange, pink, green
What structure connects the cerebral hemispheres?
Corpus callosum
What are gyri?
Elevated ridges of tissue
What are gyri separated by?
Shallow grooves called sulci
What is a fissure?
Deeper groove that separates large portions of the brain
What is the longitudinal fissure?
Separates the cerebral hemispheres
What is the transverse cerebral fissure?
Separates the cerebral hemispheres from the cerebellum below
How many lobes is each cerebral hemisphere divided into?
5
What is the central sulcus?
Between the frontal and parietal lobes
What is the precentral sulcus?
Anterior to the central sulcus
What is the postcentral sulcus?
Posterior to the central sulcus
What is the parieto-occipital sulcus?
Between the occipital and parietal lobes, lies deep
What is the lateral sulcus?
Outlines the temporal lobe and separates the parietal and the frontal lobes
Where is the insula?
Buried deep within the lateral sulcus
What are the five lobes of the cerebrum?
- Frontal
- Parietal
- Occipital
- Temporal
- Insula
What cortex is found in the precentral gyrus?
Primary motor cortex
What cortex is found in the postcentral gyrus?
Primary somatosensory cortex
What part of the skull does the frontal lobe sit in?
Anterior cranial fossa
What part of the skull does the temporal lobe sit in?
Middle cranial fossa
What part of the skull does the brain stem and cerebellum sit in?
Posterior cranial fossa
What are basal nuclei (WM/GM? Where are they located)?
Islands of gray matter situated deep with the white matter
What do association areas function in?
Emotional and intellectual processes
What do the basal ganglia function in?
Coordination of gross, automatic muscle movement and regulation of muscle tone
What does the limbic system function in?
Emotional aspects of behavior related to survival
What does the left hemisphere control?
- Right side’s: sensory signals, muscles, and images
- Reasoning
- Numerical and scientific skills
- Ability to use and understand sign language
- Spoken and written language
What does the right hemisphere control?
- Left side’s: sensory signals, muscles, and images
- Musical and artistic awareness
- Space and pattern perception
- Recognition of faces and emotion on faces
- Generating emotional content of language
- Generating mental images to compare spatial relationships
- Identifying and discriminating among odors
What are the three areas of the frontal lobe?
Primary motor cortex, Broca’s motor speech area, prefrontal eye field area
Where is the primary motor cortex located?
Precentral gyrus
How is the primary motor cortex organized?
Somatotopic organization
What is somatotopic organization?
It is the point for point correspondence of an area of the body to a specific area of the CNS
What are larger areas of the primary motor cortex devoted to? What is an example?
Larger areas for muscle groups that do skilled motions (example, hands and mouth)
What does Broca’s area produce?
Speech
Which hemisphere is Broca’s area usually found in?
Left
What does damage to the Broca’s area result it?
Broca’s aphasia or expressive aphasia, comprehension is fine, but the patient has difficulty articulating
What does the prefrontal eye field area control?
Voluntary eye movement
What personal characteristics are controlled by the frontal lobe?
Behavior and personality
What are the major areas of the parietal lobe?
Primary somatosensory cortex, primary gustatory area
Where is the primary somatosensory cortex located?
Postcentral gyrus
How is the primary somatosensory cortex organized?
Somatotopic organization
What are larger areas of the primary somatosensory cortex devoted to? What is an example?
Body areas with a larger number of sensory receptors (example, fingertips and mouth)
What is the major area of the occipital lobe?
Primary visual cortex
What are the primary areas of the temporal lobe?
Primary auditory area, Wernicke’s area
Where is Wernicke’s area precisely located?
Within the temporal and parietal lobes
What does Wernicke’s area do?
It interprets the meaning of words - provides comprehension
What does damage to the Wernicke’s area result in?
Wernicke’s aphasia or receptive aphasia - trouble with comprehension
What does the insula function in?
Interoception, gut feelings, info about homeostatic balance, addiction, emotions
What is interoception?
Somatic sensation that is oriented inward or viscerally
What are some examples of places to feel interoception?
Heart, lungs, GI tract
What are some examples of gut feelings?
Hunger, thirst, air hunger
What are some examples of information about homeostatic balance?
Temperature, pain, sexual arousal, itch, muscle ache, crude to touch, sensual touch
What two things coemerge at the insula?
Conscious physical sensation and conscious emotional awareness
What are some examples of emotions that arise from the insula?
Love/lust, hate, disgust, humiliation, guilt, gratitude
What kind of neurons are found in the cerebral cortex?
Interneurons
What does the cerebral cortex control?
Conscious mind - awareness of self, sensation, communication, understanding, voluntary movement
How many layers does the cerebral cortex have?
6 layers - 40% of the brains mass
What are the three kinds of cortex areas?
Sensory, motor, association
Where is the cortex found (lobe)?
All lobes of the brain
What is the cortex connected by?
Association fibers