Antiarrhythmics Flashcards Preview

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Flashcards in Antiarrhythmics Deck (30)
1

Class 2 acts on what phase of cardiac action potential

Phase 4
Beta blockers
Prolongs PR interval

2

Class 3 acts on what phase of cardiac action potential

Phase 3
K channel blockers
Prolongs QT interval

3

Class 4 acts on what phase of cardiac action potential

Phase 2
CCBs
Prolongs PR interval

4

Class 1A antiarrhythmics
(Prolongs AP duration)

Procainamide
Disopyramide
Quinidine

5

Class 1B antiarrhythmics
(shortens AP duration)

Lidocaine
Mexiletine
Tocainide
Phenytoin

6

Class 1C antiarrhythmics

Flecainide
Propafenone
Encainide
Moricizine

7

Class 2 antiarrhythmics

Propranolol
Esmolol

8

Class 3 antiarrhythmics

Dofetilide
Sotalol
Amiodarone

9

Class 4 antiarrhythmics

Verapamil
Diltiazem

10

Miscellaneous antiarrhythmics

Adenosine

11

Causes lupus-like syndrome

Procainamide

12

Has marked antimuscarinic effects

Disopyramide

13

Cause cinchonism (headache, vertigo, tinnitus) and ITP

Quinidine

14

Treatment of class 1A overdose

Na lactate

15

DOC for ventricular arrhythmias post-MI; used for digoxin-induced arrhythmias

Class 1B

16

Used in neuropathic pain

Mexiletine

17

Causes agranulocytosis

Tocainide

18

Drugs that cause agranulocytosis

CCCAPPIT
Clozapine
Cotrimoxazole
Colchicine
Aminopyrine
Phenylbutazone
PTU
Indomethacin
Tocainide

19

Used for refractory arrhythmias; contraindicated for post-MI arrhythmias

Flecainide

20

Post-MI prophylaxis against sudden death; used for thyrotoxicosis

Propranolol

21

Used for acute perioperative and thyrotoxic arrhythmias; used in SVT

Esmolol

22

Treatment and prophylaxis of atrial fibrillation; causes torsades de pointes

Dofetilide

23

Indication for sotalol

Afib
SVT

24

Used for refractory arrhythmias; most efficacious of all antiarrhythmics

Amiodarone

25

Why are dihydropyridine CCBs not useful as antiarrhythmics?

Evokes reflex tachycardia

26

Used for SVT and migraine; causes gingival hyperplasia

Verapamil

27

Used for SVT and raynaud's phenomenon

Diltiazem

28

DOC for paroxysmal SVT; causes hypotension and transient chest pain

Adenosine

29

Effective in some cases of torsades de pointes

Magnesium ion

30

Class 1 acts on what phase of cardiac action potential

Phase 0
Na channel blockers
Prolongs QRS duration