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Flashcards in Antihelmithic Drugs Deck (20)
1

DOC for E. granulosus

Albendazole

2

DOC for ascariasis, ancylostoma, necator, and capillariasis

Albendazole

3

DOC for trichuris

Mebendazole

4

DOC for enterobius

Pyrantel pamoate

5

DOC for strongyloides

Ivermectin

6

DOC for wuchereria and brugia

DEC

7

DOC for trichinella

Thiabendazole

8

DOC for hydatid disease

Albendazole

9

Drug of choice for filariasis and eye worm disease

DEC

10

May cause Mazzotti reaction

DEC
Ivermectin

11

DOC for roundworm and hookworm infections

Pyrantel pamoate

12

Praziquantel is contraindicated in?

Ocular Cysticercosis

13

Contraindicated in pregnancy

Mebendazole
Ivermectin
Thiabendazole

14

DOC for all cestodes except E. granulosus

Praziquantel

15

MOA of praziquantel

Increases membrane permeability to calcium, causing marked contraction initially and then paralysis of trematode and cestode muscles; this is followed by vacuolization and parasite death

16

MOA of pyrantel pamoate

Stimulates nicotinic receptors present at neuromuscular junctions of nematodes

17

MOA of mebendazole

Selectively inhibits microtubule synthesis and glucose uptake in nematodes

18

MOA of ivermectin

Intensifies GABA-mediated neurotransmission in nematodes and causes immobilization of parasites

19

MOA of DEC

Immobilizes microfilariae

20

MOA of albendazole

Inhibits microtubule assembly