Antiprotozoal Drugs Flashcards Preview

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Flashcards in Antiprotozoal Drugs Deck (37)
1

Blood schizonticides

Chloroquine
Quinine

2

Gametocides

Primaquine

3

Sporonticides

Proguanil
Pyrimethamine

4

May precipitate porphyria

Chloroquine

5

Used for chloroquine-resistant malaria

Quinine
Atovaquone-Proguanil
Sulfadixine-Pyrimethamine

6

Used for severe falciparum malaria

Quinidine

7

Causes cinchonism, hemolysis in G6PD deficiency, and blackwater fever

Quinine
Quinidine

8

DOC for malaria in pregnant patients

Quinine

9

Chemoprophylaxis in chloroquine-resistant areas

Mefloquine

10

Used for acute attacks of falciparum malaria

Quinine

11

Used for the radical cure of P. vivax ans P. ovale
Terminal prophylaxis (vivax, ovale)

Primaquine

12

Chemoprophylaxis for multi drug resistant malaria

Doxycycline

13

Causes tooth enamel dysplasia/discoloration

Doxycyline

14

Can cause nightmares

Halofantrine
Lumefrantine

15

Cardiotoxic (prolongs PR and QT interval)

Halofantrine
Lumefrantine

16

DOC for uncomplicated falciparum malaria in the Philippines

Artemeter-Lumefrantine

17

Malaria chemoprophylaxis for chloroquine-sensitive areas

Chloroquine 500mg/tab, 1 tab weekly

18

Malaria chemoprophylaxis for chloroquine-resistant areas

Mefloquine 250mg/tab, 1 tab weekly

19

Malaria chemoprophylaxis for MDR areas

Doxycycline 100mg/tab, 1 tab daily

20

Areas of MDR malaria

Palawan
Davao del Norte
Compostella Valley

21

Tissue schizonticides

Primaquine

22

Tissue amebicides

Chloroquine
Emetines
Metronidazole
Tinidazole

23

Luminal amebicides

Diloxanide furoate
Iodoquinol
Paromomycin

24

DOC for asymptomatic carrier of E. histolytica

Diloxanide furoate

25

Amebicide which causes thyroid enlargement

Iodoquinol

26

DOC for severe intestinal and extraintestinal amebiasis

Metronidazole

27

Causes metallic taste, dark urine, and disulfiram reaction

Metronidazole

28

Amebicide which causes congenital deafness

Paromomycin

29

DOC for cryptosporodiosis

Nitazoxanide

30

Drug of choice for prophylaxis and treatment of pneumocystosis

Co-trimoxazole

31

Drug of choice for prophylaxis and treatment of toxoplasmosis

Pyrimethamine+Clindamycin

32

DOC for advanced west african sleeping sickness

Eflornithine

33

DOC for african sleeping sickness

Melarsoprol

34

DOC for Chagas disease

Nifurtimox

35

DOC for leishmaniasis

Sodium stibogluconate

36

First line drug for early west african sleeping sickness

Pentamidine

37

First line drug for early east african sleeping sickness

Suramin