Antiprotozoal Drugs

Question 1

Blood schizonticides

Answer 1

Chloroquine

Quinine

Question 2

Gametocides

Answer 2

Primaquine

Question 3

Sporonticides

Answer 3

Proguanil

Pyrimethamine

Question 4

May precipitate porphyria

Answer 4

Chloroquine

Question 5

Used for chloroquine-resistant malaria

Answer 5

Quinine
Atovaquone-Proguanil
Sulfadixine-Pyrimethamine

Question 6

Used for severe falciparum malaria

Answer 6

Quinidine

Question 7

Causes cinchonism, hemolysis in G6PD deficiency, and blackwater fever

Answer 7

Quinine

Quinidine

Question 8

DOC for malaria in pregnant patients

Answer 8

Quinine

Question 9

Chemoprophylaxis in chloroquine-resistant areas

Answer 9

Mefloquine

Question 10

Used for acute attacks of falciparum malaria

Answer 10

Quinine

Question 11

Used for the radical cure of P. vivax ans P. ovale
Terminal prophylaxis (vivax, ovale)

Answer 11

Primaquine

Question 12

Chemoprophylaxis for multi drug resistant malaria

Answer 12

Doxycycline

Question 13

Causes tooth enamel dysplasia/discoloration

Answer 13

Doxycyline

Question 14

Can cause nightmares

Answer 14

Halofantrine

Lumefrantine

Question 15

Cardiotoxic (prolongs PR and QT interval)

Answer 15

Halofantrine

Lumefrantine

Question 16

DOC for uncomplicated falciparum malaria in the Philippines

Answer 16

Artemeter-Lumefrantine

Question 17

Malaria chemoprophylaxis for chloroquine-sensitive areas

Answer 17

Chloroquine 500mg/tab, 1 tab weekly

Question 18

Malaria chemoprophylaxis for chloroquine-resistant areas

Answer 18

Mefloquine 250mg/tab, 1 tab weekly

Question 19

Malaria chemoprophylaxis for MDR areas

Answer 19

Doxycycline 100mg/tab, 1 tab daily

Question 20

Areas of MDR malaria

Answer 20

Palawan
Davao del Norte
Compostella Valley

Question 21

Tissue schizonticides

Answer 21

Primaquine

Question 22

Tissue amebicides

Answer 22

Chloroquine
Emetines
Metronidazole
Tinidazole

Question 23

Luminal amebicides

Answer 23

Diloxanide furoate
Iodoquinol
Paromomycin

Question 24

DOC for asymptomatic carrier of E. histolytica

Answer 24

Diloxanide furoate

Question 25

Amebicide which causes thyroid enlargement

Answer 25

Iodoquinol

Question 26

DOC for severe intestinal and extraintestinal amebiasis

Answer 26

Metronidazole

Question 27

Causes metallic taste, dark urine, and disulfiram reaction

Answer 27

Metronidazole

Question 28

Amebicide which causes congenital deafness

Answer 28

Paromomycin

Question 29

DOC for cryptosporodiosis

Answer 29

Nitazoxanide

Question 30

Drug of choice for prophylaxis and treatment of pneumocystosis

Answer 30

Co-trimoxazole

Question 31

Drug of choice for prophylaxis and treatment of toxoplasmosis

Answer 31

Pyrimethamine+Clindamycin

Question 32

DOC for advanced west african sleeping sickness

Answer 32

Eflornithine

Question 33

DOC for african sleeping sickness

Answer 33

Melarsoprol

Question 34

DOC for Chagas disease

Answer 34

Nifurtimox

Question 35

DOC for leishmaniasis

Answer 35

Sodium stibogluconate

Question 36

First line drug for early west african sleeping sickness

Answer 36

Pentamidine

Question 37

First line drug for early east african sleeping sickness

Answer 37

Suramin