antibiotics Flashcards

(39 cards)

1
Q

what does benzyl penicillin treat and how is it administered?

A

mostly gram positive

  • strep. pneumoniae
  • strep. pyogenes

some gram negative
-neisseria meningitidis

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2
Q

what do amoxicillin and ampicillin treat and how are they administered?

A

gram negative coliforms (that don’t produce beta lactamase)
gram positives
-streptococci
-enterococci

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3
Q

what does co-amoxiclav treat?

A

same as amoxicillin but in addition it treats beta lactamase producing coliforms

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4
Q

what does flucloxicillin treat?

A

staphylococcus infections

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5
Q

what does piperacillin treat?

A

extended gram negative cover (broad spectrum)

useful for treating:

  • pseudomonas spp.
  • enterococcus faecalis
  • anaerobes
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6
Q

what is pip/taz?

A

a combination of piperacillin and tazobactam to provide beta lactamase producung organisms cover

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7
Q

what do the carbapenems treat?

A

broad spectrum including anaerobes

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8
Q

what do the cephalosporins treat?

A

both gram negative and positive
positive action decreases with increasing generations
negative action increases with increasing generations

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9
Q

what generation cephalosporin is cephradime and what is it good at treating?

A

1st gen,

good at treating gram positive

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10
Q

what generation cephalosporin is cefuroxime and what is it good at treating?

A

2nd gen.

average for both negative and positive

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11
Q

what generation cephalosporin is ceftriaxone and what is it good at treating?

A

3rd gen.

good at treating gram negative

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12
Q

what generation cephalosporin is ceftazidime and what is it good at treating?

A

3rd. gen
good at treating gram negative
also has activity against pseudomonas spp

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13
Q

why must care be taken when prescribing ceftazidime?

A

it is a cephalosporin so can cause C. Difficile infections

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14
Q

what is vancomycin used to treat and how is it administered?

A

gram positive only
treats MRSA and C. Difficile
given orally and IV

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15
Q

what is teicoplanin used to treat and how is it administered?

A

gram positive only.

given parenterally

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16
Q

what is gentamicin used to treat and how is it administered?

A

mostly gram negative
inc. pseudomonas and coliforms
also staph. (not strep. though)
given parenterally

17
Q

what is azithromycin used to treat?

A

single dose chlamydia treatment

18
Q

what are clarithromycin and erythromycin used to treat?

A
mainly gram positive
also organisms causing atypical pneumonia 
eg. chlamydia psittacci
coxiella burnetti
mycoplasma pneumonia
legionella pneumophillia
19
Q

what do linezolid and daptomycin treat?

20
Q

what does clindamycin treat?

A

grams positive: strep and staph

21
Q

why must care be taken when prescribing clindamycin?

A

it can cause pseudomembranous colitis which is associated with a C. Diff infection

22
Q

what is fusidic acid used to treat?

A

staphylococcus, used along with fluclox.

23
Q

what are the tetracyclins used to treat?

A

broad spectrum

24
Q

what is trimethoprim used to treat on its own?

25
what are trimethoprim and sulphamothaxozole used to treat when they are combined?
chest infections
26
what is ciprofloxacin used to treat?
gram negative | can treat pseudomonas infections aswell
27
what is levofloxacin used to treat?
Gram negative and also has action against strep. pneumoniae so can be used for chest infections
28
what is nalidixic acid used to treat?
UTIs
29
what is metronidazole used to treat?
anaerobes | including C. Diff and bacteriodes
30
what is nitrofurantoin used to treat?
UTIs caused by gram negative, excluding proteus and pseudomonas
31
what is fidoxamicin used to treat?
C. Difficile
32
what are the general side effects of beta lactams
thrush, allergic reactions, encephalopathy and convulsions
33
what are the side effects of vancomycin?
ototoxicity nephrotoxicity skin rashes
34
what are the side effects of gentamicin?
ototoxicity and renal toxicity
35
what are the side effects of linezolid?
bone marrow suppression and lowering platelet count
36
why must car be taken when prescribing ciprofloxacin?
it can cause C. Diff
37
which organ is flucloxacillin toxic to?
liver
38
what are the side effects of trimethoprim?
haematological toxicity
39
which drugs cause reversible peripheral neuropathy?
metronidazole and nitrofurantoin