Flashcards in antiviral drugs Deck (24):
what are the anti herpes drugs ?
which of the anti herpes drugs are nucleoside analogues that interfere with nucleic acid synthesis?
what are the anti-HIV drugs?
3 used together:
which drugs are used against chronic Hepatitis B and C infections?
which drugs are used against viral respiratory infections?
what does aciclovir treat and how is it administered?
HSV and VZV (varicella zoster virus)
it is given IV for severe infections eg. VZV pneumonitis and hereps encephalitis
orally and topically for HSV
what are famiclovir and valaciclovir used to treat and how are they administered?
HSV and Shingles
what is ganciclovir used to treat?
CMV- life and sight threatening infections
what is valganciclovir used to treat?
prodrug if ganciclovir so can be given orally to treat CMV
what is the toxicity of ganciclovir and valganciclovir?
toxic to bone marrow
what is foscarnet used to treat?
HSV, VZV and CMV resistant to nucleoside analogues
how is foscarnet administered?
what is the toxicity of foscarnet?
what is cidofovir used to treat?
how does zidovudine affect the HIV virus?
it is a nucleoside analogue so interferes with nucleic acid synthesis
how does nevirapine affect the HIV virus?
non-nucleoside reverse transcriptase inhibitor
how does saquinavir affect the HIV virus?
what is Interferon-α used to treat and how is it administered?
selected chronic hep. B and C infections, administered subcutaneously
what are side affects of Interferon-α?
what is rabavavin used to treat?
chronic hep. C occasionally for severe respiratory syncytial virus (RSV)
how is ribabvavin administered?
what is lamivudine used to treat and how is it administered?
mainly HIV but also Hep. B
what is adefovir used to treat and how is it administered?