Flashcards in Antimicrobial chemotherapy side affects of common agents Deck (37)
which organims is benzyl penicillin used against?
gram positive, eg pneumococcal, miningococcal, and strep. pyogenes infections
how is benzyl penicillin administered?
amoxicillin and ampicillin
treats gram negative infections, also treats streptococci, enterococcal and some coliforms
mode of administration for amoxicillin and ampicillin
what does co-amoxiclav treat?
normal range for amoxicillin (gram negative, streptococci and some coliforms) plus β-lactamase producing coliforms
what does flucloxacillin treat?
staphylococcal infections as is resistant to staph. β-lactamase action.
what does Piperacillin treat?
extended gram negative cover, also acts against enterococcus faecalis and pseudomonas also has anti-anaerobic activity.
imipenem and meropenem
active against most bacteria, including anaerobes
which organisms do cephalosporins act against?
gram negative and gram positive
1st generation cephalosporin
2nd generation cephalosporin
3rd generation cephalosporin
ceftriaxone and ceftazidime
how does action against gram negative organisms change with increasing generations of cephalosporins?
how does action against gram positive organisms change with increasing generations of cephalosporins?
which species can ceftazidime act against that other cephalosprorins can't?
which oganisms are aminoglycosides, such as gentamicin, used against?
act against gram negative organisms including pseudomonas. also acts against most staphylococci but not streptococci?
how are aminoglycosides administered?
which organisms do glycopeptides such as vancomysin and teicoplanin act against?
only gram positive
how are glycopeptides adiministered?
which organisms do macrolides such as clarithromycin and erythromycin act against?
mainly gram positive and organisms causing atypical pneumonia
what is the macrolide azithromycin used for?
used against single dose treatment of chlamydia
which organisms do quinolones act against?
acts against nearly all gram negative organisms
first generation quinolone
second generation quinolone
third generation quinolone
what does metronidazole act against?
effective against anaerobes both gram positive and negative
what does fusidic acid act against?
only acts against staphylococcal drug, useful against staphylococcal osteomyelitis and pneumonia
what is trimethoprim used to treat?
urinary tract infections
what is co-trimoxazole?
a combination of trimethoprim and sulfamethoxazole