Antimicrobial chemotherapy side affects of common agents Flashcards Preview

Principles of disease (Ross Lilley) > Antimicrobial chemotherapy side affects of common agents > Flashcards

Flashcards in Antimicrobial chemotherapy side affects of common agents Deck (37)
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1

which organims is benzyl penicillin used against?

gram positive, eg pneumococcal, miningococcal, and strep. pyogenes infections

2

how is benzyl penicillin administered?

IV

3

amoxicillin and ampicillin

treats gram negative infections, also treats streptococci, enterococcal and some coliforms

4

mode of administration for amoxicillin and ampicillin

oral absorption

5

what does co-amoxiclav treat?

normal range for amoxicillin (gram negative, streptococci and some coliforms) plus β-lactamase producing coliforms

6

what does flucloxacillin treat?

staphylococcal infections as is resistant to staph. β-lactamase action.

7

what does Piperacillin treat?

extended gram negative cover, also acts against enterococcus faecalis and pseudomonas also has anti-anaerobic activity.

8

imipenem and meropenem

active against most bacteria, including anaerobes

9

which organisms do cephalosporins act against?

gram negative and gram positive

10

1st generation cephalosporin

cephradine

11

2nd generation cephalosporin

cefuroxime

12

3rd generation cephalosporin

ceftriaxone and ceftazidime

13

how does action against gram negative organisms change with increasing generations of cephalosporins?

activity increases

14

how does action against gram positive organisms change with increasing generations of cephalosporins?

activity decreases

15

which species can ceftazidime act against that other cephalosprorins can't?

pseudomonas species

16

which oganisms are aminoglycosides, such as gentamicin, used against?

act against gram negative organisms including pseudomonas. also acts against most staphylococci but not streptococci?

17

how are aminoglycosides administered?

parenterally

18

which organisms do glycopeptides such as vancomysin and teicoplanin act against?

only gram positive

19

how are glycopeptides adiministered?

parenterally

20

which organisms do macrolides such as clarithromycin and erythromycin act against?

mainly gram positive and organisms causing atypical pneumonia

21

what is the macrolide azithromycin used for?

used against single dose treatment of chlamydia

22

which organisms do quinolones act against?

acts against nearly all gram negative organisms

23

first generation quinolone

nalidixic acid

24

second generation quinolone

ciprofloxacin

25

third generation quinolone

levofloxacin

26

what does metronidazole act against?

effective against anaerobes both gram positive and negative

27

what does fusidic acid act against?

only acts against staphylococcal drug, useful against staphylococcal osteomyelitis and pneumonia

28

what is trimethoprim used to treat?

urinary tract infections

29

what is co-trimoxazole?

a combination of trimethoprim and sulfamethoxazole

30

what is co-trimoxazole used to treat?

chest infections, as does not cause clostridium infections