Bio Ch 9 Flashcards

(47 cards)

0
Q

Interphase

A

majority of the cell cycle

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1
Q

Cell cycle

A

orderly set of stages that take place between the time a eukaryotic cell divides and the time the resulting daughter cells also divide

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2
Q

Chromatid

A

double helix of DNA

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3
Q

Sister chromatids

A

2 identical chromatids

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4
Q

Mitosis

A

nuclear division

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5
Q

Cytokinesis

A

division of the cytoplasm

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6
Q

Mitotic spindle

A

during mitosis, daughter chromosomes are distributed by this to 2 daughter nuclei

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7
Q

Signal

A

agent that influences the activities of a cell

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8
Q

Growth factors

A

signaling proteins received at the plasma membrane

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9
Q

Cyclins

A

family of internal signaling proteins; increase and decrease as the cell cycle continues

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10
Q

p53

A

signaling protein in mammalian cells that stops the cycle at the G1 checkpoint when DNA is damaged (# = molecular weight in kilodaltons)

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11
Q

Apoptosis

A

programmed cell death

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12
Q

RB

A

protein responsible for interpreting growth signals and also nutrient availability signals; retinoblastoma, a cancer of the retina that occurs when this gene undergoes a mutation

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13
Q

Caspases

A

enzymes that bring about apoptosis

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14
Q

Somatic cells

A

body cells

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15
Q

Histones

A

proteins that are especially involved in organizing chromosomes

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16
Q

Chromatin

A

when a eukaryotic cell is not undergoing division, the DNA and associated proteins are located within this, which has the appearance of a tangled mass of thin threads

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17
Q

Diploid (2N) number

A

full number of chromosomes that is found in all cells of the individual; 2 chromosomes of each kind

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18
Q

Haploid (n) number

A

half the diploid number; contains only 1 chromosome of each kind; only sperm and eggs have this number of chromosomes in the life cycle of animals

19
Q

Centromere

A

sister chromatids are constricted and attached to each other at this region

20
Q

Kinetochores

A

protein complexes that develop on either side of the centromere during cell division

21
Q

Centrosome

A

main microtubule organizing center of the cell; divides before mitosis begins

22
Q

Centrioles

A

barrel-shaped organelles; pair in each centrosome in an animal cell; not found in plant cells

23
Q

Prophase

A

nuclear division is about to occur; chromatin has condensed and the chromosomes are visible; nucleolus disappears and the nuclear envelope fragments; spindle begins to assemble as 2 centrosomes migrate away from one another

24
Asters
array of microtubules radiates toward the plasma membrane from the centrosome; serve to brace the centrioles during later stages of cell division
25
Prometaphase
preparations for sister chromatid separation are evident; kinetochores appear on each side of the centromere (attach sister chromatids to the kinetochore spindle fibers)
26
Metaphase
centromeres of chromosomes are in alignment on a single plane at the center of the cell
27
Metaphase plate
an imaginary plane that is perpendicular and passes through the circle in the center of the cell; indicates the future axis of cell division
28
Anaphase
2 sister chromatids of each duplicated chromosome separate at the centromere, giving rise to 2 daughter chromosomes; shortest phase of mitosis
29
Telophase
the spindle disappears as new nuclear envelopes form around the daughter chromosomes
30
Cleavage furrow
indentation of the membrane between 2 daughter nuclei, forms as anaphase draws to a close
31
Cell plate
newly formed plasma membrane that expands outward until it reaches the old plasma membrane and fuses with it; in plant cells
32
Therapeutic cloning
used to produce human tissues; can begin with adult stem cells or embryonic stem cells
33
Reproductive cloning
production of a new individual
34
Cancer
cellular growth disorder that occurs when cells divide uncontrollably
35
Benign
not cancerous
36
Malignant
cancerous & possesses the ability to spread
37
Tumor
abnormal cancer cells pile on top of one another and grow in multiple layers; most aggressive cell becomes the dominant cell of this
38
Metastasis
spread of cancer from the place of origin throughout the body; caused by the ability of cancer cells to migrate and invade tissues
39
Angiogenesis
additional mutations occur in tumor cells, allowing them to direct the growth of new blood vessels into the tumor
40
Proto-oncogenes
code for proteins that promote the cell cycle and prevent apoptosis; likened to the gas pedal of a car because they cause the cell cycle to speed up
41
Tumor suppressor genes
code for proteins that inhibit the cell cycle and promote apoptosis; often linked to the brakes of a car because they cause the cell cycle to go more slowly or even stop
42
Oncogenes
Cancer-causing genes
43
Telomeres
ends of chromosomes
44
Asexual reproduction
offspring are genetically identical to the parent
45
Nucleoid
electron-dense, irregularly shaped region of bacterial chromosomes; not enclosed by a membrane
46
Binary fission
asexual reproductive process of prokaryotes; division (fission) produces 2 (binary) daughter cells that are identical to the original parent cell