CHROMOSOMES

Question 0

Most common cytogenetic abnormality of meningioma?

Answer 0

Deletion of region 12 on chr22

Question 1

Oligodendrogliomas responding to chemotherapy

Answer 1

19q and 1p deletion

Question 2

Most common genetic abnormality in medulloblastoma?

Answer 2

Duplication of 17q

Question 3

Beta amyloid

Answer 3

Chr21

Question 4

Presenlin1

Answer 4

Chr14

Question 5

Presenilin2

Answer 5

Chr1

Question 6

Huntington disease

Answer 6

Chr4

Question 7

Prion protein

Answer 7

Chr20

Question 8

APC gene

Answer 8

Chr5

Question 9

Peutz jegher

Answer 9

Chr19(STK2) serine threonine kinase

Question 10

Hemochromatosis

Answer 10

HFE 6p

Question 11

Neuroblastoma

Answer 11

Loss of 1p
Loss of 11q
Gain of 17q

Question 12

Widening of mediastinum seen in which infection

Answer 12

Pulmonary anthrax(Hemorrhagic lymphadenitis)

Question 13

M7 AML

Answer 13

t(1;22)

Question 14

Gold standard of neuromuscular monitoring

Answer 14

Mechanomyography

Question 15

Drugs causing hyperglycaemia

Answer 15

Diazoxide
Interferon beta
Atypical antipsychotics
Propranolol
Pentamidine 
Protease inhibitors 
Encainide
Thiazides 
Eptoin
Steroid

Question 16

ABO gene

Answer 16

Chr9

Question 17

Lewis gene

Answer 17

Chr19

Question 18

Gorlin syndrome

Answer 18

Chr9

Patch gene

Question 19

ATM

Answer 19

Chr11

Question 20

Amphicytes are seen in

Answer 20

ATM

Question 21

Prolonged bleeding from circumcision site and bloody diarrhoea in infancy

Answer 21

Wiskott Aldrich syndrome

Question 22

Named type 4 hypersensitivity reactions

Answer 22

Jones mote(basophils hypersensitivity)
Frei(LGV)
Fairley

Question 23

Named type 1 hypersensitivity reactions

Answer 23

Casoni
Theobald smith
Schultz dale
Prausnitz kustner

Question 24

Jones mote reaction

Answer 24

Cutaneous basophils hypersensitivity | Not a type 4 reaction

Question 25

Most sensitive test for DIC

Answer 25

FDP level

Question 26

Flea bitten kidney

Answer 26

Malignant hypertension | Petechial hemorrhages on kidney surface

Question 27

Ewing sarcoma

Answer 27

Translocation of 22q EWS GENE | More common t(11;22)(q24;q12)

Question 28

Cystinosis

Answer 28

Chr17

Question 29

Swanneck deformity of PCT

Answer 29

Cystinosis

Question 30

Favourable cytogenetic markers in ALL

Answer 30

Trisomy 4,10,17 | t(12;21)

Question 31

Unfavourable prognostic markers in ALL

Answer 31

Hypodiploidy t(1;19) t(4;11) t(9;22)

Question 32

Marfan syndrome

Answer 32

Chr5 chr15 fibrillin

Question 33

Machado Joseph disease

Answer 33

SCA 3 | Chr 14

Question 34

SCA type 2

Answer 34

Chr12

Question 35

Marker positive during window period of hepatitis B

Answer 35

IgM anti HBc

Question 36

Barlow syndrome

Answer 36

MVP

Question 37

Most common leaflet to be affected in MVP

Answer 37

Posterior leaflet

Question 38

MVP murmur increases on

Answer 38

Standing

Question 39

ECG in MVP

Answer 39

Biphasic or inverted T Waves in inferior leads

Question 40

EEG in encephalopathies

Answer 40

``` FIRDA frontal intermittent rhythmic delta activity Periodic epileptiform discharges Triphasic waves(-+-) ```

Question 41

EEG IN hypsarrythmia

Answer 41

Chaotic | West syndrome

Question 42

EEG IN Maple syrup urine disease

Answer 42

comb wave pattern

Question 43

EEG IN absent seizures

Answer 43

3Hz spike dome pattern

Question 44

EEG IN herpes simplex encephalitis

Answer 44

PLED periodic lateralised epileptiform discharges

Question 45

Most definitive urinary finding in acute pyelonephritis

Answer 45

WBC casts

Question 46

Most common cause of pyelonephritis in Community Hospital

Answer 46

E.coli

Question 47

Most common cause of pyelonephritis in ICU

Answer 47

Candida

Question 48

Renal papillary necrosis

Answer 48

``` Pyelonephritis Obstruction Sickle cell anaemia Tuberculosis Cirrhosis Analgesic nephropathy Renal vein thrombosis DM systemic vasculitis ``` POSTCARDS

Question 49

Emphysematous pyelonephritis

Answer 49

DM

Question 50

Xanthogranulomatous pyelonephritis

Answer 50

Obstruction

Question 51

FRC IS BELOW closing volume in

Answer 51

Hyaline membrane disease

Question 52

Normal relation FRC RV CCV

Answer 52

FRC> CCV >RV

Question 53

Catastrophic APS

Answer 53

APS involving 3 or more organ systems

Question 54

Diagnostic criteria for APS

Answer 54

Sappora criteria

Question 55

Antibodies in APS

Answer 55

Anti cardiolipin Anti beta 2 glycoprotein Lupus anticoagulant

Question 56

Clotting tests prolonged in APS

Answer 56

aPTT KCT kaolin clotting time dRVVT

Question 57

Treatment of catastrophic APS

Answer 57

IVIg Rituximab LMWH

Question 58

Williams syndrome

Answer 58

Chr7 | Elastin

Question 59

Beta hemoglobin chain

Answer 59

Chr11

Question 60

Alpha hemoglobin chain

Answer 60

Chr16

Question 61

Wilson disease

Answer 61

Chr13

Question 62

VHL

Answer 62

Chromosome 3

Question 63

PrP gene(prion)

Answer 63

Chr 20

Question 64

Noonan

Answer 64

Chrosome12

Question 65

Myotonic dystrophy

Answer 65

Chr19

Question 66

Friederich ataxia

Answer 66

Chr13

Question 67

Marfan

Answer 67

15q

Question 68

Wilson

Answer 68

Chr13

Question 69

Hemochromatosis

Answer 69

Chr6