DAT Immune System Cheat SHeet Flashcards

1
Q

organism’s defense system against pathogens

A

immune system

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2
Q

the first line of cellular defense and generates a rapid, nonspecific immune response

A

innate immune system

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3
Q

Physical and chemical barriers prevent pathogen entry

A

external immunity

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4
Q

first barrier to pathogens and viruses

A

skin

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5
Q

WHAT IN saliva and tears
break down microbial cell walls

A

LYSOZYME

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6
Q

Lines the lungs and sweeps invaders out

A

CILLIA

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7
Q

Stomach acid kills microbes

A

GASTRIC JUICE

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8
Q

WHAT come from stem cells in the bone marrow and can differentiate into different types of immune cells

A

luekocytes

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9
Q

Engulf foreign particles, bacteria, and dead cells via
phagocytosis

A

phagocytic leukocytes

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10
Q

Function in the destruction of
pathogens in infected tissues

A

neutrophils

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11
Q

Circulate in blood until they move
into tissues via diapedesis where they develop
into macrophages

A

monocytes

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12
Q

In tissues, they phagocytize cell
debris and pathogens and are derived from
monocytes

A

macrophages

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13
Q

Ingest pathogens and stimulate
the acquired immune response

A

dendritic cells

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14
Q

Function in an allergic response,
inflammatory response, and anaphylaxis

A

mast cells

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15
Q

Surround and destroy multicellular
parasites

A

eosinophils

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16
Q

Release histamine in the inflammatory
response and recruited to tissues when needed

A

basophils

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17
Q

Attack abnormal body cells, either tumors
or pathogen-infected cells.

A

NK cells

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18
Q

Pro-Tip: Relative abundance of the Leukocytes:

A

Neutrophils > Lymphocytes > Monocytes > Eosinophils

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19
Q

Are secreted by infected
cells that stimulate neighboring cells to
produce proteins to defend against viral
infections

A

interferons

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20
Q

Chemical signaling molecules
used in the immune response for cell-cell
communication

A

cytokines

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21
Q

Specific type of cytokine

A

Interleukins

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22
Q

IL 1 involved in…

A

inflammatory response

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23
Q

il2 triggers …

A

adaptive immune response

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24
Q

contains complement proteins that circulate the body and assist in activating the immune response

A

complement system

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25
critical to innate immunity and they are key proteins that link innate and acquired immunity
toll like receptors
26
Innate Immune cells have toll-like receptors that recognize...
molecular patterns that many pathogens have
27
if toll like receptors are inhibited, what happens
immune system is inhibited
28
last line of immune defense that develops after the body has been attacked.
adaptive immune system
29
immune response targets specific antigens.
adaptive immunity
30
specific foreign pathogen or molecule that can trigger an immune response
antigen
31
a specific part of an antigen to which an antibody binds
epitope
32
Proteins that bind to a specific antigen they recognize
antigen
33
Primary cells of the adaptive immune response
lymphocyte
34
originate in the bone marrow and concentrate in lymphatic tissue such as lymph nodes, thymus gland, and spleen
lymphocytes
35
originate and mature in the bone marrow, and are activated in response to foreign antigens
B cells
36
glycoproteins produced by B cells that are specific to an antigen
anitbodies
37
5 classes of antibodies
IgA, IgD, IgE, IgG, and IgM
38
what shape are antibodies
Y
39
how many chains of a B cell
2 heavy and 2 light
40
how are chains linked for b cells
disulfide bond
41
When a foreign antigen activates a B cell, what occurs
proliferation
42
what happens once proliferation occurs
daughter B cells produced
43
B cells that circulate in the blood and release specific free antibodies that dispose of antigens by agglutination, inactivation, opsonization, and lysis
plasma cells
44
Long-lived B cells that store memory of an antigen they have encountered.
memory cells
45
originate in the bone marrow but mature in the thymus, and have antigen receptors
t cells
46
4 types of t cells
Cytotoxic T cells, Helper T cells, Suppressor T cells, memory t cells
47
killer T cells that destroy by releasing perforin protein and via lysis
cytotoxic t cells
48
stimulate activation of B cells, cytotoxic T cells, and suppressor T cells
helper t cells
49
play a negative feedback role in the immune system
suppressor t cells
50
similar in function to Memory B cells
memory T cells
51
If an individual doesn’t have a functioning thymus, they would not be able to produce...
t cells
52
Active and passive immunity are two divisions of...
adaptive immunity
53
Acquired after direct exposure to an infection/vaccine:
active immunity
54
Antibodies made after exposure to pathogen
natural active immunity
55
antibodies made after exposure to a vaccine
artificial active immunity
56
Acquired from external sources:
passive immunity
57
Antibodies transferred from mother to baby
natural passive
58
antibodies given vi serum injection
articialr passive immunity
59
The three types of antigen presenting cells
macrophages, dendritic cells and b cells
60
what are both possible pathways for the adaptive immune system to regulate an immune response
Cell-mediated and humoral response
61
(antibody-mediated response)
humoral response
62
occurs when pathogens are recognized in the blood or lymph
humoral response
63
critical to humoral response
b cells
64
occurs when an infected cell is recognized and bound by a T-cell
cell mediated response
65
which cells are critical to cell mediated response
T cells