Derm Flashcards

1
Q
A

Symmetric Lupoid Onychodystrophy

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2
Q
A

Eosinophilic Granuloma Complex
Indolent “Rodent” Ulcer

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3
Q
A

Feline Acne

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4
Q
A

Miliary Dermatitis

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5
Q
A

Traumatic Alopecia

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6
Q
A

Recurrent Bacterial Pyoderma

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7
Q
A

Alopecia X

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8
Q
A

Sebaceous Adentitis
Follicular Casting

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9
Q
A

Superficial Necrolytic Dermatitis

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10
Q
A

Bacterial Furunculosis

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11
Q

Differentials?

A

DLE
Pemphigus
Epitheliotrophic Cutaneous T Cell Lymphoma

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12
Q
A

Eosinophilic Folliculitis

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13
Q
A

Vitiligo

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14
Q
A

Xeromycteria

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15
Q
A

Uveodermatologic Syndrome
VKH-Like Syndrome

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16
Q
A

Erythema Multiforme
TMS Reaction

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17
Q
A

Vasculitis

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18
Q

What causes SLO?

A

Idiopathic
Immune-mediated

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19
Q

How is SLO diagnosed?

A

Clinical signs
Biopsy (requires amputation of P3)

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20
Q

How is SLO treated?

A

Pentoxifylline (30mg/kg BID)
Omega 3s (60mg/kg SID)
Cyclosporine (5mg/kg SID)
Doxy/niacinamide
Steroids

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21
Q

What is the prognosis of SLO?

A

Treatment takes 3-6 months, can be lifelong
Goal is to eliminate pain and fracture
Nails will be dystrophic forever

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22
Q

What causes superficial necrolytic dermatitis?

A

Severe liver disease
Cutaneous manifestation of cirrhosis

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23
Q

How is superficial necrolytic dermatitis diagnosed?

A

Liver failure
“Swiss cheese liver”
Hypoalbuminemia
Diabetes
Skin biopsy

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24
Q

What does superficial necrolytic dermatitis look like on histopathology?

A

Red: parakeratotic hyperkeratosis
White: edema (necrolysis)
Blue: epidermal hyperplasia

25
How is superficial necrolytic dermatitis treated?
Manage underlying cause Diet (egg yolk, zinc, FAs, ultamino, EL?) Amino acids IV weekly
26
What causes indolent ulcers?
Antigen driven eosinophilic infiltrate within skin and/or oral cavity
27
What are differential diagnoses for indolent ulcers?
SCC Trauma
28
How are indolent ulcers treated?
Can be abx responsive
29
What is the pathogenesis of feline acne?
Focal abnormality of keratinization/possibly lipid production
30
How is feline acne diagnosed?
Cytology (malassezia, bacteria) Deep skin scrape +/- trichogram (demodex) Dermatophyte culture +/- PCR
31
How is mild/moderate feline acne treated?
Benign neglect Dermoscent (topical fatty acids) Duoxo calm (phytosphingosines) Seborrhea shampoos (sulfur/salicylic acid, benzoyl peroxide)
32
How is moderate/severe feline acne treated?
Mupirocin Oral/injectable G (+) antibiotic +/- Systemic steroid
33
What are causes of traumatic feline alopecia?
Fleas Atopy Food Bacterial pyoderma Dermatophytosis Ectoparasitism Demodex Malassezia Underlying irritation Hyperthyroidism Psychogenic
34
What causes recurrent bacterial pyoderma?
Allergy Endocrinopathy Immunocompromise
35
How is recurrent bacterial pyoderma treated?
Primary disease control PLUS Topical abx preferred (3x/week, then 2x/wk for maintenance)
36
How long should superficial pyoderma be treated?
3 weeks (1 week after resolution of clinical signs)
37
How long should deep pyoderma be treated?
4 - 6 weeks (2 weeks after resolution of clinical signs)
38
What is the cause of alopecia X?
Follicular signaling problem
39
How is alopecia X diagnosed?
Biopsy - flame follicles (catagen hairs with tricholemmal keratin at follicular base
40
How is alopecia X treated?
Benign neglect Neutering Melatonin Triolostane? Deslorelin? Microneedling?
41
What causes sebaceous adenitis?
Immune-mediated disease targeting sebaceous glands (absence)
42
How is sebaceous adenitis diagnosed?
Biopsy - no sebaceous glands
43
How is sebaceous adenitis treated?
Topical mineral oil Systemic cyclosporine Duoxo seborrhea shampoo
44
How is bacterial furunculosis treated?
4-6 weeks of systemic antibiotics Topical antimicrobial prevention Control underlying cause Cyclosporine?
45
What is the initial diagnostic plan for facial dermatoses?
Cytology Deep skin scrape Fungal culture/PCR *Biopsy for noninfectious causes*
46
How is eosinophilic folliculitis and furunculosis treated?
Prednisone 2 mg/kg SID for 1 week, then taper
47
What is the pathogenesis of vitiligo?
Melanocyte destruction Non-inflammatory
48
How is vitiligo treated?
No treatment - cosmetic Requires sunscreen
49
How is nasal hyperkeratosis treated?
50
What is the pathogenesis of xeromycteria?
Loss of parasympathetic innervation to lateral nasal gland *Otitis media*
51
What drugs are most commonly associated with cutaneous drug eruptions?
NSAIDs Penicillins Cephalosporins
52
Describe the concept of diascopy
Blanching = inflammation Non-blanching = hemorrhage
53
What is the pathogenesis of VKH-like syndrome?
Immune-mediated disease that attacks melanocytes
54
How is VKH-like syndrome treated?
Treat eyes first!!! Cyclosporine (derm) Mycophenolate (eyes)
55
What is the pathogenesis of erythema multiforme?
Immune-mediated destruction (apoptosis) of keratinocytes
56
How is EM treated?
Remove cause Topical, systemic antimicrobials Pred Cyclosporine
57
What is the pathogenesis of vasculitis?
Increased permeability (edema, hemorrhage, ischemia)
58
How is vasculitis treated?