ENDOCRINE: TEST 1 NOTES Flashcards
Hormone that has anti-inflammatory effect
Cortisol
Cushing’s Syndrome from chronic steroid use: What is important to remember when trying to discontinue the steroids?
Steroids should be tapered off slowly, NEVER STOPPED ABRUPTLY.
Pheochromocytoma: Appropriate nursing action
a. weight
b. palpate skin for warmth
c. test urine for glucose
d. monitor BP
d. monitor BP
- Rare tumor of the Adrenal Medulla (also chest, bladder, abd, brain)
- Excessive catecholamines (up to 14mcg/100mL)
- Causes HTN
- Causes death if untreated
Pheochromocytoma
Main Catecholamines (3)
- Dopamine
- Epinephrine
- Norepinephrine
“Classic Triad” of Symptoms
- Diaphoresis (profuse sweating)
- Severe headache
- Palpitations
Primary treatment for Pheochromocytoma
Adrenalectomy (surgical removal)
Diagnostic Labs for Pheochomocytoma: 24h urine collection will reveal elevated levels of (3)
- VMA (vanillylmandelic acid)
- Metanephrine
- Catecholamines
Normal range of Catecholamines (per 100mL) - urine sample
14mcg/100mL
Pheochromocytoma: Diagnosic Procedures to locate tumor
- CT Scan
3. MRI
Pheochromocytoma: Excessive amounts of (1)__ and __ are secreted from the (2)__.
- epinephrine and norepinephrine (catecholamines)
2. Adrenal Medulla
Main complications of Pheochromocytoma (4)
- Hypertensive Crisis
- Dysrhythmias
- Myocardial Infarction
- Stoke
Hormone that prolongs and intensifies the Sympathetic Nervous System to stress
Epinephrine
Characterized by:
- Excessive Cortisol secretion
- Caused by increased ACTH from the Pituitary
Cushing’s Disease
Characterized by:
- Chronic/excessive Cortisol production
- Caused by administration of Glucocorticoids in large doses for several weeks or longer
Cushing’s Syndrome
Main interventions for Hyperthyroidism/Grave’s Disease (6)
- Adequate REST (HTN)
- Cool, quiet environment (heat intolerance)
- Diet - high calorie (inc. metab.)
- Admin - Antithyroid Meds
- Admin - Sedatives
- Daily WEIGHT (weight loss)
- Do not admin STIMULANTS (HTN)
- Occurs with Type 1
- Rapid decrease in glucose at night, that generates release of counterregulatory hormones = HYPERglycemia evident in the morning
- Tx: Decrease interm-insulin dose in evening, or bedime snack
Somogi Phenomenon
Cushing Syndrome S/S
- Muscle wasting, weakness
- Buffalo hump, moon face
- Large Abd, thin extremities
- Fragile skin
- Hirsutism
- High sugar and sodium
- Low Potassium and Calcium
Diagnostic assessment for Hypoparathyroidism: Carpal spasm by compressing brachial artery (Hypocalcemia)
Trousseau’s Sign