ENDOCRINE: TEST 1 NOTES Flashcards

1
Q

Hormone that has anti-inflammatory effect

A

Cortisol

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2
Q

Cushing’s Syndrome from chronic steroid use: What is important to remember when trying to discontinue the steroids?

A

Steroids should be tapered off slowly, NEVER STOPPED ABRUPTLY.

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3
Q

Pheochromocytoma: Appropriate nursing action

a. weight
b. palpate skin for warmth
c. test urine for glucose
d. monitor BP

A

d. monitor BP

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4
Q
  • Rare tumor of the Adrenal Medulla (also chest, bladder, abd, brain)
  • Excessive catecholamines (up to 14mcg/100mL)
  • Causes HTN
  • Causes death if untreated
A

Pheochromocytoma

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5
Q

Main Catecholamines (3)

A
  1. Dopamine
  2. Epinephrine
  3. Norepinephrine
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6
Q

“Classic Triad” of Symptoms

A
  1. Diaphoresis (profuse sweating)
  2. Severe headache
  3. Palpitations
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7
Q

Primary treatment for Pheochromocytoma

A

Adrenalectomy (surgical removal)

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8
Q

Diagnostic Labs for Pheochomocytoma: 24h urine collection will reveal elevated levels of (3)

A
  1. VMA (vanillylmandelic acid)
  2. Metanephrine
  3. Catecholamines
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9
Q

Normal range of Catecholamines (per 100mL) - urine sample

A

14mcg/100mL

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10
Q

Pheochromocytoma: Diagnosic Procedures to locate tumor

A
  1. CT Scan

3. MRI

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11
Q

Pheochromocytoma: Excessive amounts of (1)__ and __ are secreted from the (2)__.

A
  1. epinephrine and norepinephrine (catecholamines)

2. Adrenal Medulla

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12
Q

Main complications of Pheochromocytoma (4)

A
  1. Hypertensive Crisis
  2. Dysrhythmias
  3. Myocardial Infarction
  4. Stoke
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13
Q

Hormone that prolongs and intensifies the Sympathetic Nervous System to stress

A

Epinephrine

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14
Q

Characterized by:

  • Excessive Cortisol secretion
  • Caused by increased ACTH from the Pituitary
A

Cushing’s Disease

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15
Q

Characterized by:

  • Chronic/excessive Cortisol production
  • Caused by administration of Glucocorticoids in large doses for several weeks or longer
A

Cushing’s Syndrome

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16
Q

Main interventions for Hyperthyroidism/Grave’s Disease (6)

A
  1. Adequate REST (HTN)
  2. Cool, quiet environment (heat intolerance)
  3. Diet - high calorie (inc. metab.)
  4. Admin - Antithyroid Meds
  5. Admin - Sedatives
  6. Daily WEIGHT (weight loss)
  7. Do not admin STIMULANTS (HTN)
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17
Q
  • Occurs with Type 1
  • Rapid decrease in glucose at night, that generates release of counterregulatory hormones = HYPERglycemia evident in the morning
  • Tx: Decrease interm-insulin dose in evening, or bedime snack
A

Somogi Phenomenon

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18
Q

Cushing Syndrome S/S

A
  1. Muscle wasting, weakness
  2. Buffalo hump, moon face
  3. Large Abd, thin extremities
  4. Fragile skin
  5. Hirsutism
  6. High sugar and sodium
  7. Low Potassium and Calcium
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19
Q

Diagnostic assessment for Hypoparathyroidism: Carpal spasm by compressing brachial artery (Hypocalcemia)

A

Trousseau’s Sign

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20
Q

Diagnostic assessment for Hypoparathyroidism: Facial muscle spasms by tapping facial nerve (anterior to ear)

A

Chvostek’s Sign

21
Q

Two potential complications specific to Parathyroidectomy

A
  1. Airway Obstruction
  2. HYPOcalcemia
    (Potential removal of part of Thyroid > which produces Calcitonin)
22
Q
Pt taking levothyroxine (Synthroid)
Complaints:
Cold intolerance
Weight gain
Dry Skin
Puffy Eyes
Physician Orders...
A

Increase dosage (Pt is still experiencing low thyroid hormone levels) after checking the T4 level

23
Q

Congenital Hypothyroidism: Severe lack of TH during fetal life and infancy

A

Cretinism

24
Q

Hyperthyroidism: Medication to help with tremors and tachycardia

A

propranolol

25
Q

Addisonian Crisis can be precipitated by (5)

A
  1. Stress
  2. Infection
  3. Trauma
  4. Surgery
  5. Rapid withdrawal of corticosteriod use
26
Q
Transsphenoidal Hypophysectomy POST-OP:
Monitor for any postnasal drip. 
(1) May indicate \_\_\_
(2) Check drainage for \_\_
(3) If positive, it is likely \_\_
A
  1. Leakage of CSF
  2. Glucose
  3. CSF
27
Q

Pheochormocytoma Adrenalectomy PRE-OP:

Priority Nursing Action is to monitor ___

A

Vital Signs (+Epinephrine = increased HTN)

28
Q

Thyroidectomy POST-OP:

(1) Maintain Pt in __ position
(2) Monitor site for __ and __
(3) Check dressing __ and ___.

A
  1. Fowler’s (90)
  2. Edema and bleeding
  3. anteriorly and back of neck
29
Q

Very low Thyroid production

A

myxedema

30
Q

Adults with myxedema have (1)__ appetite, with weight (2)__.

A
  1. decreased
  2. gain
    (because of decreased metabolism)
31
Q

Pheochromocytoma: Diet

A

High calorie, vitamins, minerals

32
Q

Pheochromocytoma: Avoid (3)

A
  1. Smoking
  2. Caffeine
  3. Sudden position changed
33
Q

Tiredness, Constipation, Cold intolerance, and Weight gain are symptoms of:

a. hyperthyroidism
b. hypothyroidism

A

b. hypothyroidism

34
Q

Excessive Corticosteriod production will cause the inflammatory response to increase/decrease

A

decrease/suppress

Cortisol = ANTI-inflammatory

35
Q

Inflammation = Response to fight off infection

A

Avoid people with infections

36
Q

Adrenal Crisis (extreme hypofunction) is an Emergency, and death may result from __ and __.

A

hypotension and vasomotor collapse

37
Q

Too much Insulin production results in which condition:

a. DI
b. DM
c. hypoglycemia
d. hyperglycemia

A

c. hypoglycemia

38
Q

Exophthalmos may be present in

a. hyperparathyroidism
b. hyperthyroidism

A

b. hyperthyroidism

39
Q

Thyroid Storm:

3 Classic Signs

A
  1. Fever
  2. Tachycardia
  3. Hypertension
40
Q

Aspirin increases/decreases serum levels of T3 and T4

A

increases

41
Q

Thyroid Storm (hyperthyroid): What should NOT be given to reduce Pt fever, and what should be given instead?

A

Aspirin (increases T3 and T4)

Acetaminophen should be given.

42
Q

Which hormone increases heart rate and force contraction?

A

Epinephrine

43
Q

Hyperpituitarism: Excess secretion of GH in adults results in a condition called

a. Acromegaly
b. Addison’s Disease
c. Hashimoto’s Disease
d. Cushing’s Disease

A

a. Acromegaly

44
Q

Contraceptives interfere with the activity of bromocriptine mesylate (Parlodel)

A

Parodel

45
Q

Parlodel therapy is indicated in the treatment of __.

A

Acromegaly

46
Q

__ therapy, alone or as adjunctive therapy with pituitary irradiation or surgery, reduces serum growth hormone by 50% or more in approximately ½ of patients treated, although not usually to normal levels.

A

Parodel

47
Q

Propylthiouracil (PTU) causes (1)__. Therefore, the client is advised to contact the HCP if a (2)___.

A
  1. agranulocytosis

2. fever or sore throat develops

48
Q

Propylthiouracil (PTU) is a __

A

Antithyroid Medication

49
Q

What hormone is secreted, in response to a high serum calcium level?

A

Calcitonin