prelim genetics lesson 2 intro to gen Flashcards

1
Q

Derived from the Greek root “Gen” which means “to __” or “to__”.

A

become or grow into

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2
Q

Branch of biology concerned with the

A

study of inheritance

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3
Q

study of inheritance,

A

genetics

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4
Q

Why family members look alike

A

GENETICS

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5
Q

Why some diseases like diabetes or cancer run in families.

A

GENETICS

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6
Q

What makes you unique, or one of a kind.

A

GENETICS

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7
Q

proposed the theory that a
moist vapor descends from the brain,

A

Pythagoras (500 B.C)

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8
Q

proposed the theory that
each parent produces ‘a semen’ which
arises directly from various parts of the body.

A

Empedocles

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9
Q

thought that the semen of men has some “Vitalizing” effect and he considered it as the highly purified blood.

A

Aristotle

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10
Q

According to him the mother furnishes
inert matter and the father gives the life- giving power, “dynamic” to the new life

A

Aristotle

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11
Q

He believed that inheritance was conveyed via the blood

A

Aristotle

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12
Q

The PREFORMATION theory was proposed by two Dutch biologists,

A

Swammerdam and Bonnet (1720-
1793).

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13
Q

This theory states that a miniature human called “homunculus ” was already preformed in the egg and sperm.

A

PREFORMATION THEORY

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14
Q

The development of zygote
resulted only in the growth of a miniature human who was already present in the egg and sperm.
However, this theory was rejected because this could

A

not be proved scientifically.

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15
Q

THEORY OF EPIGENETICS was proposed by ___ a German biologist and it states that egg or sperm cells do not contain miniature human

A

Wolff (1738- 1794),

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16
Q

gametes contained undifferentiated living substance capable of forming the organized body after fertilization. This proposition was called as

A

epigenetic concept

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17
Q

THEORY OF ACQUIRED CHARACTERS This concept was proposed by ____ a French biologist.

A

Lamarck (1744-1829)

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18
Q

new character once
acquired by an individual shall pass on
to its progeny.

A

Lamarck

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19
Q

This theory was disproved by __.He cut the tail of mice for successive generations and always got the baby mice with tail. Thus, this theory was rejected .

A

Weismann; THEORY OF ACQUIRED CHARACTERS

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20
Q

This theory THEORY OF PANGENES was proposed by __, an English naturalist.

A

Charles Darwin (1809 – 1882)

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21
Q

According to him, each part of the animal body produces a minute copy of its own, called

A

gemmule or pangene

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22
Q

theory of pangenesis is also known as
the “___”.

A

theory of blending inheritance

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23
Q

He developed the theory of natural
selection,

A

Charles Darwin

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24
Q

the idea that members of a
population who are better adapted to their environment will be the ones most likely to survive and pass their traits on to the next generation.

A

theory of natural selection

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25
On the Origin of Species by Means of Natural Selection
(1859)
26
This theory GERMPLASM THEORY was advocated by ____ a German biologist.
August Weismann (1834-1914),
27
According to this theory, organism’s body contains two types of cells namely
somatic cells and reproductive cells.
28
The somatic cell form the ___ and its various organ systems, while the reproductive cells form __ and ___.
body , sperm and ova.
29
somatic cells contain the___ and reproductive cells contain the___
“somatoplasm” ; “germplasm”.
30
Changes in the somatic cells (somatoplasm), which were caused by the environment, cannot influence the germplasm and hence acquired characters are not inherited
GERMPLASM THEORY
31
Before Mendel’s experiment and ideas, Genetics was
PRE-MENDELIAN EXPERIMENTS, poorly understood
32
conducted experiments on pea much before Mendel but failed to formulate the laws of inheritance because he could not use the mathematics to his results.
Knight (1779)
33
a German botanist performed hybridization experiments in tobacco and compared the hybrids with their parents. He demonstrated that the hybrids may resemble one or the other parent or may be intermediate between them. He also showed that both the parents make equal contributions to the hybrids.
J. Kolreuter (1733-1806),
34
done experiments similar to Kolreuter and they observed the similar results. However they could not apply mathematics to their results.
Gartner and Naudin
35
developed the understanding genetics by experimenting garden peas (Pisum sativum).
Gregor Mendel
36
Father of Modern Genetics
Gregor Mendel
37
Austrian biologist, meteorologist, and Augustinian Priest
Gregor Mendel
38
wherein he showed that “factors of inheritance” are transferred from parents to offspring.
Gregor Mendel
39
Gregor Mendel conducted carefully designed experiments with nearly ____ pea plants (Pisum sativum)
30,000
40
because they are easy to grow, easy to artificially hybridize (self-pollinating plants),
pea plants (Pisum sativum)
41
has a short life cycle, with many offsprings in a single cross, and the presence of contrasting traits (alleles), and his use of pure breeds (homozygous pure lines).
pea plants (Pisum sativum)
42
* According to Mendel, genetic material of organisms exist in pairs (____) and segregate during gamete formation.
alleles
43
are responsible for observable characteristics
genotype
44
as result of fertilization.
phenotype
45
A string of complex molecules called
nucleotides
46
It contains the genetic information of life and acts as a set of instructions for how to build and maintain you.
dna
47
DNA is found in the heart of almost every human cell, in an area called the
nucleus
48
is unique, unless you’re an identical twin.
DNA
49
A short section of DNA
GENE
50
Scientists think our genetic code contains around
23,000 genes
51
Genes are instructions that our cells use to make molecules called
proteins
52
To strengthen them and keep them safe DNA is looped and coiled into a structure called a
chromosome
53
are formed before cells divide.
Chromosomes
54
An organism’s complete set of DNA
GENOME
55
An individual inherits two alleles for each gene, one from each parent.
ALLELES
56
the set of genes in our DNA which is responsible for a particular trait.
GENOTYPE
57
physical expression, or characteristics, of that trait.
PHENOTYPE
58
PP and pp are alleles of the pea plant flower color.
GENOTYPE
59
PP is for purple flowers, pp is for white flowers.
PP is for purple flowers, pp is for white flowers.
60
An organism that has the same two copies of a gene is considered
HOMOZYGOUS
61
An organism that has different copies of a gene
HETEROZYGOUS
62
Denoted by using capital letters. Example traits: Dark hair, Curly hair, Baldness, Widow’s peak, Freckles, Right handedness
DOMINANT
63
expressed and overrules the recessive gene.
DOMINANT
64
Denoted by using lower case letter. * Example traits: Blonde or red hair, Straight hair, Straight hairline, Round eyes, Left handedness, Blue eyes
RECESSIVE
65
Basic principles of genetics which is the transmission of genetic material from one generation to the other.
TRANSMISSION GENETICS/ CLASSICAL GENETICS
66
Focuses on individual organisms and emphasize the relationship between chromosomes and heredity,
TRANSMISSION GENETICS/ CLASSICAL GENETICS
67
* Study on the chemical nature (structure and function) of genes.
MOLECULAR AND BIOCHEMICAL GENETICS
68
Emphasize on how genetic information is encoded, replicated and processed. The cellular processes of transcription and translation gene regulation, the process that controls the expression of genetic information.
MOLECULAR AND BIOCHEMICAL GENETICS
69
Study of behavior and effects of genes in population, often using mathematical models
POPULATION AND BIOMETRICAL GENETICS
70
Focuses on the group of genes found in a population and emphasizes on how genetic composition of a group changes over time. This can include quantitative genetics and ecological genetics
POPULATION AND BIOMETRICAL GENETICS
71
Studies the influence of varying genetics on animal behavior, the effects of human disorders as well as its causes; has yielded some very interesting questions
BEHAVIORAL GENETICS
72
Diagnosis, treatment, and counseling of patients with genetic disorders or syndromes
CLINICAL GENETICS
73
6 application of genetics
* TRANSGENICS * AGRICULTURE * INDUSTRY * FORENSIC SCIENCE * HEALTH AND MEDICAL * ENVIRONMENT
74
Refers to an organism or cell whose genome has been altered by the introduction of one or more foreign DNA sequences from another species by artificial means.
TRANSGENIC
75
Provide some synthetically produced raw materials for industries
INDUSTRY
76
* Genetic fingerprinting * Forensic of crime scene * Detection of mother and father of fetus
FORENSIC SCIENCES
77
* Involves mating two members of a species each of whom possesses one or more different and desirable traits in order to create a hybrid individual possessing both traits.
Classical animal and plant breeding
78
* Chromosomal abnormalities * Production of vaccines, antibodies, vitamins, insulin * Gene therapy * Fetus designing Accurate diagnosis of diseases
HEALTH AND MEDICAL
79
Does not involve any direct manipulation of genetic material; therefore, are classified as
non-genetically modified (non-GMO).
80
Involves using enzymes and various laboratory techniques to manipulate and isolate DNA segments of interest.
Recombinant DNA technology
81
has been successfully applied to make important proteins used in the treatment of human diseases, such as insulin and growth hormone.
Recombinant DNA technology
82
mutate the DNA in a way that stops the gene’s expression permanently.
Gene knockout
83
damage specific genes, making them non-functional.
Gene knockout
84
Increase understanding of how diseases occur.
Stem cells
85
Generate healthy cells to replace cells affected by disease (regenerative medicine).
Stem cells
86
Test new drugs for safety and effectiveness.
Stem cells
87
– an organism that is a product of genetic engineering.
Genetically Modified Organism (GMO)
88
Any organism that has the genetic material from some other organism.
Transgenic
89
vehicle for transferring the recombinant DNA (altered genetic material) into the organism of interest. Ex. Plasmid and Viruses
Vector
90
a circular DNA usually found in bacteria and yeast, commonly used for genetic engineering.
Plasmid
91
Genetic engineering, sometimes called
genetic modification,
92
is the process of altering the DNA in an organism’s genome using biotechnology tools or techniques.
​Genetic Engineering
93
Human gene that encodes for insulin production were inserted to a bacterial ___ (circular DNA) using enzymes to form the_____
plasmid; recombinant DNA
94
CRISPR means?
“Clustered Regularly Interspaced Short Palindromic Repeats”
95
is a gene-editing technology that targets specific stretches of genetic code and edit DNA at precise locations.
“CRISPR-Cas9”
96
is guided with specific guide RNA to cut at points around specific target where new gene can be inserted.
Cas9
97
is a new type of rice that contains beta carotene (provitamin A, a plant pigment that the body converts into vitamin A as needed).
Golden Rice
98
is the first cloned sheep using nuclear transfer, by transferring the nucleus from an adult mammary gland cell into an unfertilized premature egg.
Dolly the sheep
99
* Dolly is named after the country singer, * Dolly the sheep died at the age of
Dolly Parton; 6