Sympathomimetics Flashcards Preview

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Flashcards in Sympathomimetics Deck (16):
0

Drug for cardiac arrest and anaphylaxis
Non-selective, direct acting sympathomimetic

Epinephrine

1

Nonselective, direct acting sympathomimetic
Drug of last resort for neurogenic shock & cardiogenic shock
Vasoconstricts renal blood vessels
SE: reflex bradycardia

Norepinephrine

2

Non-selective, direct acting sympathomimetic
Drug for shock, heart failure
Vasodilation in splanchnic and renal vessels via D1

Action is dose-dependent

Dopamine

3

Drug for asthma
Beta nonselective sympathomimetic
Competitive inhibitor of propranolol
SE: Arrhythmia, CV disturbance

Isoproterenol

4

Selective Alpha1 agonist
Drug for decongestion
SE: rebound nasal congestion, if given >3 days
Mydriasis without Cycloplegia with ophthalmic administration

Phenylephrine

Vs Atropine (Mydriasis with cycloplegia)

5

Selective Alpha 2 agonists

Methyldopa
Apraclonidine
Clonidine

MAC

6

Alpha2 selective
Drug for hypertension, acts centrally
SE: rebound hypertension

Clonidine

7

Tx for rebound hypertension from Clonidine

Phentolamine

Prevention: taper use prior to discontinuation

8

Alpha2 selective
Drug for pre-eclampsia
SE: hemolytic anemia (+ coombs)

Methyldopa

9

Alpha 2 selective
Drug for glaucoma
Decreases aqueous humor secretion
SE: BOV, dry mouth, conjunctivitis

Apraclonidine
(Brimonidine)

10

Beta1 selective
Drug for acute heart failure, cardiogenic shock
SE: Tachyphylaxis, tachycardia, arrhythmia
May be used in cardiac stress testing

Dobutamine

11

Beta2 selective
Drug of choice for acute asthma attacks
Also used for tocolysis of preterm labor
Can precipitate arrhythmia in pxs with COPD and heart disease

Albuterol/Salbutamol
Terbutaline, Ritodrine (for tocolysis)

12

Sympathomimetic of choice:
To increase CO in acute HF and septic shock

B1 and D1
Dobutamine and Dopamine

13

Sympathomimetic of choice:
Vasoconstriction in hemostasis/decongestion

A1 agonist

14

Sympathomimetic of choice:
Temporary BP maintenance in spinal shock
Hypertension
Glaucoma

A2 agonist

16

Sympathomimetic of choice:
Bronchodilation
Uterine Smooth Muscle Relaxation

B2 agonist