7.2 - Adrenaline Flashcards Preview

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Flashcards in 7.2 - Adrenaline Deck (30):
1

What is the preparation of adrenaline?

Comes in an ampoule - 1mg in 1ml

2

What does adrenaline stimulate?

Alpha and Beta receptor.

3

What is the mechanism of action of adrenaline?

Is an Alpha and Beta receptor agonist.

Also stabilises mast cells membranes and reduces histamine release from mast cells.



4

What cells are stabilised by adrenaline?

Mast cells membranes.

5

What happens to the Alpha cells when adrenaline is used?

Alpha stimulation causes vasoconstriction of vascular smooth muscle, increasing peripheral resistance.


6

What happens to the Beta cells when adrenaline is used?

Beta one stimulation causes increased heart rate and stronger contractions which gives a stronger cardiac output.



Beta two stimulation causes bronchodilation.

7

What are the indications for use of adrenaline?

cardiac arrest
anaphylaxis
severe asthma
severe bradycardia
septic shock unresponsive to volume loading
stridor (nebulised)
smoke inhalation (nebulised)
chemical inhalation (nebulised)

8

What are the contraindications of adrenaline?

None - other than universal contraindications.

9

What are the relative contraindications of adrenaline?

myocardial ischaemia
tachydysrhythmias

10

What is the onset of effect of adrenaline if given intramuscularly?

3 - 5 minutes

11

What is the onset of effect of adrenaline if given through a nebuliser?

Instant - on contact with target site

12

What is the onset of effect of adrenaline if given through an IV?

5 - 20 seconds

13

What is the duration of effect of adrenaline?

Cardiovascular effects last 2 - 15 minutes.
Mast cell membranes effects last up to several hours.

14

What are some common adverse side effects of adrenaline?

tachycardia
tachydysrhythmias
myocardial iscaemia
ventricular ectopy
hypertension
nausea
vomiting
tremor
headache
anxiety

15

Does adrenaline interact with anything?

Yes - may require increased doses if a patient is taking beta blockers and/or calcium agonists.

16

If giving adrenaline as an IM injection - is it used diluted or undiluted?

Undiluted

17

If using adrenaline in a nebuliser do you need to add any saline with it?

No - use undiluted.

18

Fill the gap:
Adrenaline administration can make a patient ............... and look and feel.............


tachypnoeic
awful

19

What is the IM adrenaline dose for a 5kg/3 month old child for anaphylaxis and asthma?

0.05mg Dose
0.5ml of 1/10000 Volume
(1/10,000 = 1mg adrenaline + 9ml 0.9% NaCl)

20

What is the IM adrenaline dose for a 10kg/1 year old child for anaphylaxis and asthma?

0.1mg Dose
0.1ml undiluted Volume

21

What is the IM adrenaline dose for a 20kg/5 year old child for anaphylaxis and asthma?


0.2mg Dose
0.2ml undiluted Volume

22

What is the IM adrenaline dose for a 30kg/10 year old child for anaphylaxis and asthma?

0.3mg Dose
0.3ml undiluted Volume

23

What is the IM adrenaline dose for a 40kg/13 year old child for anaphylaxis and asthma?

0.4mg Dose
0.4ml undiluted Volume

24

What is the IM adrenaline dose for an adult for anaphylaxis and asthma?

0.3mg - 0.5mg Dose (depending on size of patient)

25

What is the IM adrenaline dose for a 5kg/3 month old child for anaphylaxis and asthma?

0.05mg Dose
0.5ml of 1/10000 Volume
(1/10,000 = 1mg adrenaline + 9ml 0.9% NaCl)

26

What is the IM adrenaline dose for a 10kg/1 year old child for anaphylaxis and asthma?

0.1mg Dose
0.1ml undiluted Volume

27

What is the IM adrenaline dose for a 20kg/5 year old child for anaphylaxis and asthma?


0.2mg Dose
0.2ml undiluted Volume

28

What is the IM adrenaline dose for a 30kg/10 year old child for anaphylaxis and asthma?

0.3mg Dose
0.3ml undiluted Volume

29

What is the IM adrenaline dose for a 40kg/13 year old child for anaphylaxis and asthma?

0.4mg Dose
0.4ml undiluted Volume

30

What is the IM adrenaline dose for an adult for anaphylaxis and asthma?

0.3mg - 0.5mg Dose (depending on size of patient)

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