Drugs for Cough

Question 1

MUCOLYTICS

reduces disulfide bridges that bind glycoproteins to other proteins such as albumin

Answer 1

N-Acetylcysteine (NAC)
Carbocisteine
Ambroxol
Bromhexine

Question 2

Used in the management of acetaminophen toxicity

Answer 2

N-Acetylcysteine (NAC)

Question 3

EXPECTORANT

irritant to gastric vagal receptors and recruit efferent parasympathetic reflexes that cause glandular exocytosis of a less viscous mucus mixture

Answer 3

Guiafenesin

Question 4

ANTITUSSIVES

Centrally Acting (Opioid)

decreased sensitivity of the MEDULLARY/CNS COUGH CENTERS to peripheral stimuli and decreased mucosal secretion

SE: constipation

Answer 4

Dextromethorphan

Codeine

Question 5

Indicated only in INTRACTABLE cough from bronchial carcinoma

Answer 5

Morphine

Question 6

ANTITUSSIVES

ANTITUSSIVES

Centrally Acting (Non - Opioid)

Act through RECEPTORS IN THE BRAINSTEM to (-) cough

Answer 6

Butamirate Citrate

Question 7

ANTITUSSIVES

Peripherally Acting

Non-opioid drug with a peripheral action by (-) the afferent pathways that generate the cough reflex (MODULATES C-FIBER ACTIVITY)

Answer 7

Levodropropizine

Question 8

(-) PDE III and (-) calcium entry

potent anti inflammatory agent and acts via COX2 (-)

Answer 8

Lagundi (Vitex Negundo)