Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology > Opioid Analgesics and Antagonists > Flashcards

Opioid Analgesics and Antagonists Flashcards

1
Q

FULL AGONIST

A

FHM3

FENTANYL- MOST POTENT
Sufentanil, Alfentanil, Remifentanil, Ohmefentanyl

HEROIN

MORPHINE
Hydromorphone
Oxymorphone

METHADONE
Luvomethadyl acetate
Levorphanol

MEPERIDINE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

DOC for MI pain

A

MORPHINE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

DOC for OPIOID WITHDRAWAL

A

METHADONE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

DOC for BILIARY PAIN/PANCREATIC PAIN

A

MEPERIDINE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Fentanyl + Droperidol

A

neurolepticanalgesia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Actions of Morphine

A

HEC of a DREAM

Histamine release
Emesis
CV hypotension

Depression of CNS, GIT, cough center
Respiratory Depression
Euphoria
Analgesia
Miosis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

PARTIAL AGONISTS - also used as antitussives

A

HYDROCODONE
OXYCODONE
DEXTROMETHORPHAN
CODEIN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

WEAK AGONISTS

A

PROPOXYPHENE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

MIXED-AGONIST ANTAGONISTS

partial mu receptor agonist
antagonist at kappa and delta receptors

A 
BUPRENORPHINE
Nalbuphine
Butorphanol
Pentazocine
Levallorphan
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

ANTAGONISTS

A

NALOXONE
Naltrexone
Nalmefene
Methylnatrexone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

DUAL ACTING

weak agonist at mu receptor

(-) neuronal reuptake of serotonin and NE

(-) pain neurotransmission

for moderate pain, adjuncts to opioid

A

TRAMADOL
Tapentadol

SE: 
seizures
nausea
dizziness
pruritus
constipation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

NATURAL

A

Morphine
Codeine
Thelaine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

SEMI SYNTHETIC

A 
Heroin
Apomorphine
Hydrocodone
Oxycodone
Hydromorphone
Oxymorphone
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

PURELY SYNTHETIC

A 
Methadone
Loperamide
Meperidine
Fentanyl
Tramadol
Pentazocine
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Full Agonists

PHENANTHRENES

strong agonist at mu receptors

for severe pain (MI, cancer, pulmonary edema)

A

Morphine
Hydromorphone
Oxymorphone
Heroin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Full Agonists

PHENYLPIPERIDINE

A 
Fentanyl
Sufentanil
Alfentanil
Remifentanil
Ohmefentanyl
17
Q

Opioid with the SHORTEST half life

A

Remifentanil (3-4 mins)

18
Q

Opioid with the LONGEST half life

A

Buprenorphine (4-8 hrs)

19
Q

Full Agonists

PETHIDINE

strong agonist at mu and kappa receptors

for postoperative shivering

A

Meperidine

SE:
seizures
delirium

does NOT cause miosis rather mydriasis

20
Q

Meperidine + MAOI

A

Hyperpyrexic coma

21
Q

Meperidine + SSRI

A

Serotonin syndrome

22
Q

Full Agonists

PHENYLHEPTYLAMINES

strong agonist at mu receptors
NDMA antagonist

for opioid dependence

A

Methadone
Levomethadyl Acetate
Levorphanol

23
Q

Mixed agonist and antagonist used for POSTOPERATIVE SHIVERING

A

Butorphanol

24
Q

Mixed agonist and antagonist used for OPIOID WITHDRAWAL STATES

A

Buprenorphine

25
Q

Opioid antagonist

DOC for Opioid overdose

A

Naloxone

26
Q

Opioid antagonist

for opioid and alcohol dependence

A

Naltrexone

Pharmacology (72 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions