Serotonergic Agents Flashcards
1
Q
5-HT1D
brain
blood vessels
A
vasoconstriction
modulate NT release
2
Q
5-HT1D Agonist
DOC for acute migraine
A
-TRIPTAN
Sumatriptan Almotriptan Eletriptan Frovatriptan Naratriptan Rizatriptan Zolmitriptan
3
Q
ALL 5-HT1D agonist are PER OREM EXCEPT
A
Sumatriptan - intranasal
4
Q
5-HT3
brain
A
CTZ - vomiting
5
Q
5-HT3 Antagonist
A
-SETRON
Ondansetron Granisetron Dolasetron Palonosetron Alosetron
6
Q
5-HT4
GIT
A
increased motility
7
Q
5-HT4 Agonist
for IBS but WITHDRAWN - cardiotoxic
A
Tegaserod
8
Q
5-HT2
blood vessels
A
vasoconstriction
9
Q
5-HT2 Antagonist (Vasoselective)
for migraine, cluster headache
A
Ergotamine
Dihydroergotamine
Methylsergide
10
Q
5-HT2 Antagonist (Uteroselective)
also has partial alpha and dopamine agonist
for postpartum bleeding
A
Ergonovine
Methylergonovine
11
Q
5-HT2C Agonist - POMC
appetite suppressants
A
Lorcaserin
