Nitroimidazoles Flashcards

1
Q

Prodrug

Converted in anaerobic organisms by the redox enzyme pyruvate-ferredoxin oxidoreductase

reactive reduction by FERREDOXIN forming free radicals that disrupt ETC

A

Metronidazole

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2
Q

Nitroimidazole

A

Metronidazole
Tinidazole
Secnidazole

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3
Q

Adverse Effects of Nitroimidazole

A

GIT disturbances

DRY MOUTH, FURRY TONGUE

METALLIC TASTE

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