Flashcards in Exam 2 Miscellaneous Deck (26)
Coagulative necroses are seen in ______.
Liquefactive necroses are seen in ______.
brain and spleen
______ does not protect against reactive oxygen species, but glutathione peroxidase, catalase, and superoxide dismutase do.
Does platelet activating factor have systemic effects?
Factor XII manifests with pain because ________.
it activates kallikrein which in turn converts kinin to bradykinin
Factor XII activates _____.
What does granulation tissue do?
It lays down the framework on which new epithelium can be laid, but it does not re-epithelialize.
I-CAM helps ________.
leukocytes migrate into tissues
Selectins help ______, while integrins help ______.
in rolling; in adhesion
Fibroblast proliferation, macrophages, and neo-vascularization would be seen in ______.
What makes D-dimer levels increase?
Breakdown of fibrin in clotting
Red infarctions typically affect ________.
loose tissues (like the lungs or testis), tissues with multiple blood supplies, and tissues with obstructed venous outflow
Snail, twist, and Zeb 1/2 are ______.
transcriptional repressors of E-cadherin
Anti-topoisomerase agents work by ______.
DNA double stranded breaks
Prostate cancer usually occurs in the _____.
periphery of the prostate
The type of lung cancer that is least associated with smoking is _____.
Cytotoxic agents can ________.
target a specific enzyme, but targeted agents hit specific enzymes that are faulty in cancer cells only
A cancer that has invaded regional lymph nodes but not metastasized is _____.
Tumors in the ascending colon typically _____.
protrude into the lumen
List the causes of cancer death from most to least frequent.
Infection, organ failure, thromboembolism, hemorrhage, emaciation
Aspiring overdoses involve ______.
rashes, hepatomegaly, and somnolence
What adhesion molecule normally expressed on T lymphocytes is co-opted by tumor cells?
Polyaromatic hydrocarbons metabolize to ______.
_______ is a definitive pathologic sign of alcoholic hepatitis.
Cortisol is ____ acting.