Exam 2 Miscellaneous Flashcards Preview

MS1 - Disease & Defense > Exam 2 Miscellaneous > Flashcards

Flashcards in Exam 2 Miscellaneous Deck (26):
1

Coagulative necroses are seen in ______.

heart myocytes

2

Liquefactive necroses are seen in ______.

brain and spleen

3

______ does not protect against reactive oxygen species, but glutathione peroxidase, catalase, and superoxide dismutase do.

Xanthine peroxidase

4

Does platelet activating factor have systemic effects?

No

5

Factor XII manifests with pain because ________.

it activates kallikrein which in turn converts kinin to bradykinin

6

Factor XII activates _____.

C5

7

What does granulation tissue do?

It lays down the framework on which new epithelium can be laid, but it does not re-epithelialize.

8

I-CAM helps ________.

leukocytes migrate into tissues

9

Selectins help ______, while integrins help ______.

in rolling; in adhesion

10

Fibroblast proliferation, macrophages, and neo-vascularization would be seen in ______.

granulation tissue

11

What makes D-dimer levels increase?

Breakdown of fibrin in clotting

12

Red infarctions typically affect ________.

loose tissues (like the lungs or testis), tissues with multiple blood supplies, and tissues with obstructed venous outflow

13

Snail, twist, and Zeb 1/2 are ______.

transcriptional repressors of E-cadherin

14

Anti-topoisomerase agents work by ______.

DNA double stranded breaks

15

Prostate cancer usually occurs in the _____.

periphery of the prostate

16

The type of lung cancer that is least associated with smoking is _____.

bronchioalveolar carcinoma

17

Cytotoxic agents can ________.

target a specific enzyme, but targeted agents hit specific enzymes that are faulty in cancer cells only

18

A cancer that has invaded regional lymph nodes but not metastasized is _____.

stage III

19

Tumors in the ascending colon typically _____.

protrude into the lumen

20

List the causes of cancer death from most to least frequent.

Infection, organ failure, thromboembolism, hemorrhage, emaciation

21

Aspiring overdoses involve ______.

rashes, hepatomegaly, and somnolence

22

What adhesion molecule normally expressed on T lymphocytes is co-opted by tumor cells?

CD44

23

Polyaromatic hydrocarbons metabolize to ______.

epoxides

24

_______ is a definitive pathologic sign of alcoholic hepatitis.

Alcoholic hyaline

25

Cortisol is ____ acting.

short

26

Amoeboid movement occurs _________.

quickly via collagen fibers

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