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Flashcards in Final Exam Review Deck (48):
1

Which are the zinc-dependent toxins?

Botulinum and tetanus

2

One of the first signs of schistosomiasis infection is _________.

pruritus

3

What are immunotoxins?

Toxins that are guided to certain cells (such as tumors) with antibodies

4

During the latent period, virus ____________.

is being replicated in the cell, but no virus particles are being assembled

5

Which toxin requires calcium and calmodulin to become active?

Antrax edema factor

6

What does terbinafine kill and how?

Fungus, by the accumulation of intracellular toxins

7

Nystatin is a ______ anti-fungal.

topical

8

Bacteria that require vitamins, amino acids, and growth factors are called _______.

fastidious

9

The _______ are the organs that are most affected by schistosomiasis infection.

liver and bladder

10

Bordadella pertussis works by ________.

inhibiting phagocytosis

11

tetM is transferred on ________.

conjugative transposons

12

Cholera toxin works by ______________.

raising intracellular cAMP

13

MacKonkey agars select for __________.

Gram-negative bacteria

14

Two lactose fermentators that could be found on a MacKonkey agar are __________.

E. coli and Klebsiella

15

C. diphtheria toxin results from __________.

lysogenic conversion

16

Staph food poisoning results from _______.

ingestion of preformed toxin

17

Glycocalyx is made by ________.

Staphylococcus epidermis

18

C. perfringens can also be found in _________.

healthy people

19

Gram-negative rod with intrinsic resistance to penicillin, ceftriaxone, and erythromycin?

P. aeruginosa

20

Lacking cell wall?

Mycoplasma

21

Antigenically distinct pili?

Neisseria

22

Antigenically distinct capsule?

Streptococcus pneumoniae

23

Both _____________ cannot be cultured.

chlamydia and mycoplasma

24

Spastic paralysis is _________, while flaccid paralysis is ________.

tetanus; botulinum

25

Describe bacteria on Hektoen agars.

Salmonella (green with black dots); Shigella (green with green dots); everything else (salmon)

26

The most likely bacteria to acquire erm is ______.

Staph

27

_______ can acquire gyrase mutations that induce resistance to fluoroquinolones.

Both Gram-negative and Gram-positive

28

First-generation cephalosporins have spectra of action similar to ________.

amoxicillin

29

______ can acquire mutations in PBPs.

Staph, Neis, and Strep

30

Of cephalosporins, aminoglycosides, fluoroquinolones, and erythromycin, which is least effective against P. aeruginosa?

Erythromycin

31

Aminoglycosides can kill ________.

Gram-negative aerobic bacilli

32

Which organisms can tetracyclines kill that macrolides cannot?

Gram-negative rods

33

In addition to MSSA, ______ also contains a beta-lactamase.

Klebsiella

34

Can amoxicillin kill Pseudomonas?

No! Only piperacillin can

35

B. fragilis can be killed by _________.

metronidazole, ertapenem, amoxicillin-clavulanate, tetracyclines, pip-taz, and clinamycin

36

What three drugs/drug categories kill Neisseria?

Ceftriaxone, macrolides, and tetracyclines

37

What three categories of drugs kill atypical bacteria?

Macrolides, tetracyclines, and fluoroquinolones

38

Which antibiotics inhibit the hepatic metabolism of co-administered drugs?

Erythromycin and metronidazole

39

Which fluoroquinolone is hepatically metabolized?

Ciprofloxacin

40

Which antibiotic causes oral thrush?

Doxycycline (metronidazole can exacerbate existing infections)

41

Aminoglycosides only treat ________.

Gram-negative aerobic bacilli

42

Bactrim kills _________.

Gram-positive, Gram-negative, and atypical bacteria

43

Which can kill Pseudomonas, tetracyclines or fluoroquinolones?

Fluoroquinolones

44

Which bacterial class is photosensitizing?

Doxycycline

45

Can clindamycin kill Gram-negative rods

Only Bacteroides, but primarily just Gram-positives and anaerobes

46

Can vancomycin kill Bacteroides?

Nope!

47

Compared to clarithromycin, azithromycin has the advantages of ___________.

being longer lasting, killing mycoplasma in a single dose, and does not inhibit liver enzymes

48

Which class of antibiotics can prolong QT?

Macrolides

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