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MS1 - Disease & Defense > Host-Microbe Interaction > Flashcards

Flashcards in Host-Microbe Interaction Deck (9)

Define infection.

(n.) the process whereby a microbe enters into a relationship with the host. It may or may not cause disease.


What is an infectious disease, and how does it differ from an infection?

An infectious disease is a disease caused by an infection with a microbe.Some infections are communicable; others are not communicable and are not transmitted from patient to patient.


Pathogens that affect all people equally are ________.

frank pathogens


Pathogens that affect immunocompromised hosts are termed _________.

opportunistic pathogens


Explain the distinction between mucous and mucus.

Mucus is a noun and refers to the substance secreted. Mucous is an adjective describing something (such as a "mucous membrane").


List Koch's four postulates of infectious disease.

(1) the microbe is found in characteristic lesions of the disease; (2) the microbe can be isolated and cultured in vitro from lesions; (3) the microbe can be injected into animals to mimic the disease; and (4) the specific microbes can be re-isolated from the animals


How is pathogenicity measured?

By examining the number of organisms required to be infectious in 50% of those inoculated (ID50), to produce disease in 50% of those inoculated (DD50), and to be lethal in 50% of those inoculated (LD50).


Macrophages that reside in the skin are called ________.

Langerhans cells


What is virulence?

The ability of a pathogen to cause disease in a host

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