Lec 11 Complement

Question 1

complements help blank with lysis of bacteria

Answer 1

antibody

Question 2

these can by lysed

Answer 2

gram negative bacteria and rbc

Question 3

gram positive cells are not lysed but they are blank

Answer 3

opsonized

Question 4

complement leads to blank

Answer 4

inflammation

Question 5

three complement pathways

Answer 5

classical, lectin, alternative

Question 6

the only complement with the b getting ripped off because usually a gets ripped off

Answer 6

c2

Question 7

a component with enzyme activity affecting the next piece

Answer 7

convertase

Question 8

c3 convertase

Answer 8

c4bc2a

Question 9

classical pathway involves these

Answer 9

c1,c4,c2

Question 10

alternative pathway involves these

Answer 10

factor b, d, p

Question 11

lectin pathway involves these

Answer 11

mbl, masp2, c4, c2

Question 12

pathway that can work without an antibody

Answer 12

alternative, lectin

Question 13

lectin pathway needs blank

Answer 13

sugar

Question 14

c1q in classical pathway requires blank

Answer 14

calcium

Question 15

convertase at the end of classical

Answer 15

c3

Question 16

alternative pathway doesnt involve blank activation

Answer 16

antibody

Question 17

stabilizer of alternative

Answer 17

properdin

Question 18

end of alternative pathway

Answer 18

c3 convertase

Question 19

adding c3b to c3 convertase creates blank

Answer 19

c5 convertase

Question 20

lectin pathway is like classical pathway but instead of having c1q, there is blank

Answer 20

MBL and SF

Question 21

MBL and SF blank just like c1q

Answer 21

require calcium

Question 22

c5-c9 complex is aka blank

Answer 22

membrane attack complex

Question 23

c5a, c3a, c4a are all blank

Answer 23

anaphylotoxins

Question 24

c3b, c4b, iC3b, c1q are all blank molecules

Answer 24

opsonic

Question 25

increase in c5-c9 causes blank

Answer 25

inflammation/coagulation

Question 26

factor 1, c1 inhibitor, daf, cr1 are all blank

Answer 26

complement regulators

Question 27

factor b and d blank alternative pathway

Answer 27

activate it

Question 28

factor h and I blank alternative pathway

Answer 28

inhibit it

Question 29

inhibitor of lectin pathway

Answer 29

c1INH

Question 30

c1inh deficiency is important for dentists because it can cause severe blank

Answer 30

edema

Question 31

measure the amount of each protein using traditional serologic assays

Answer 31

antigenic assay

Question 32

lytic function of the components is measured

Answer 32

functional assay

Question 33

functional assay or antigenic assay is better

Answer 33

functional

Question 34

low complement levels may mean blank

Answer 34

autoimmunity/genetic deficiency

Question 35

this complement deficiency affects all pathways

Answer 35

c3

Question 36

alternative pathway deficiency

Answer 36

pus infection

Question 37

paroxysmal nocturnal hemoblobinuria is deficiency in blank

Answer 37

daf

Question 38

c1,c4, c2 deficiency increases risk of this

Answer 38

autoimmune ct disease

Question 39

lectin pathway deficiency increases bacterial infections in blank

Answer 39

infants