Lec 7-5 - HIV Flashcards Preview

Dental Microbiology > Lec 7-5 - HIV > Flashcards

Flashcards in Lec 7-5 - HIV Deck (14):
1

hiv destroys these cells

cd4+ t lymphocytes

2

hiv 1 strains

M,O,N

3

HIV2 comes from blank

monkeys

4

this enyzme contained in the infecting virion converts positive stranded genomic rna into ds dna before going to the nucleus and integrating randomly into the chromosomes via a hiv blank

reverse transcriptase, integrase

5

hiv binds via the high affinitiy blank protein to the receptor on the host cell surface, the cd4 molecule

gp120

6

hiv1 must also bind to two coreceptors to actually enter the cell....called blank and blank

ccr5, cxcr4

7

for a mature virus, blank is required to cleave polyproteins into proteins required for viral integrity

protease

8

this gene is structural and requires cleavage by hiv protease

gag

9

this gne is cleaved by cellular proteases... not hiv proteases

env

10

not having ccr5 or cxcr4 can lead to blank

immunity from hiv infection

11

as hiv progresses, it turns into aids and the immune system regulation wanes and the patient becomes more susceptible to blank and blank

infections, malignancies

12

aids can change every base in hiv by chance alone in a blank time

very short

13

infection in hiv is usually from things that blank would usually take care of with cell mediated immunity

t cells

14

hiv progresses faster if blank

higher amount of circulating virus, low cd4 count