Lec 10 Cell Mediated Immunity Flashcards Preview

Dental Microbiology > Lec 10 Cell Mediated Immunity > Flashcards

Flashcards in Lec 10 Cell Mediated Immunity Deck (14):
1

t cell independent cell mediated responses

chemotaxis, phagocytosis, release of cytokines

2

directed movement of leukocytes along concentration gradient

chemotaxis

3

chemotaxis chemoattractant complement fragment

c5a

4

tnf alpha is a cytokine that comes from macrophages and destroys blank

tumor

5

this cytokine comes from nk cells

interferon gamma

6

Th1 key cytokine

gamma interferon

7

Th2 key cytokine

IL4

8

common denominator for antibody dependent cell mediated cytotoxicity

Fc (CD16) receptor for IgG

9

macrophages are a jack of all trades and can do all of these

non specific response, antigen presentation, effector cells

10

macrophages have a blank activation scheme because macrophages can have so many different blank

complex, effectors

11

cell mediated immunity in which the primary defense mechanism against intracellular bacteria is a macrophage

delayed type hypersensitivity (DHT)

12

three phases of delayed type hypersensitivity

cognitive (antigen recognition), activation (t cells secrete cytokines and proliferate), effector (divided into two steps

13

persistent antigen presence with continual release of cytokines and accumulation of t cells and macrophage like multinucleated cells

granulomas

14

excessive release of blank can lead to shock and hemorrhage

tnf alpha