Lec 2 - Immunoglobulins Flashcards Preview

Dental Microbiology > Lec 2 - Immunoglobulins > Flashcards

Flashcards in Lec 2 - Immunoglobulins Deck (22):
1

IgA vs IgE

Isotypes

2

Different classes of immunoglobulins

Isotypes

3

Small differences between individuals of same species in the amino acids... Ex) differences between IgA's

Allotypes

4

Most numerous immunoglobulin (85%) in serum of human

IgG

5

IgG and IgM activate blank

Complement

6

Fragments of Ig for binding

FAB

7

Ig domain that is a region of heavy or light chain which by aa sequence remains unchanged in chains of the same type

Constant

8

Ig domain that is a region that is not constant

Variable

9

Segment of heavy chain between ch1 and ch2 domainst hat is a flexible segment of aa

Hinge region

10

This is a long heavy chain that is much bigger than IgG and contains a joining chain and is the most convserved Ig

IgM

11

First Ig in immune response and produce neonate

IgM

12

This protects the Ig from proteolysis by intestinal enzymes

secretory component

13

Secretory component facilitates the transport of secretory blank into secretions

IgA

14

Major function of this Ig is to arm mast cells and basophils for their role in allergic reactions

IgE

15

IgE does not activate blank

Complement

16

Low concentration in serum and is difficult to study and acts as antigen receptor on b cells and does not activate complement

IgD

17

IgA does not have a blank component

Secretory

18

Know primary vs secondary organs

Ok

19

Thymus eliminates blank percent of all t cells

95%

20

Functions of IgG

Opsonize, agglutinate, bacterialyse

21

IgA is in anything that is secreted like these

Saliva, breastmilk, mucous

22

Antibodies were originally called blank

Gamma globulins