What is the largest body fluid compartment?
intracellular (ICF)
What are the 3 factors that are taken into consideration when evaluating a patient’s fluid balance?
1) age
2) sex
3) obesity
What are the 3 components that are concentrated in the ECF?
1) sodium
2) chloride
3) bicarbonate
T/F
The interstitial fluid compartment has a higher concentration of proteins compared to the plasma.
FALSE
A solution is separated by a semi-permeable membrane, which only allows water to cross. Side A has 1000 small particles and 100 big particles; side B has 1000 big particles. What best describes the movement of water as it follows osmotic pressure?
A) the water does not move
B) the water will move to side A
C) the water will move to side B
B
Which ions make up the bulk of the osmoles in the ICF?
sodium
chloride
If a red blood cell is placed in a hypertonic solution, what happens to the cell volume?
cell shrinks
What processes does the body use to regulate extracellular osmolality?
1) ADH - water excretion
2) Brain - water intake
What are the forces that regulate fluid movement between the plasma and interstitium?
1) osmotic pressure
2) hydrostatic pressure
Where do all alterations to body fluids being?
ECF
What happens to intracellular fluid volume and osmolality with loss of hypotonic fluid (sweating)
decrease in volume
increase in osmolality
What are 3 common ways of taking in water?
ingestion of food
ingestion of water
synthesized by oxidation
What happens to plasma sodium during hyponatremia and what are the subsequent short-term consequences to the cells?
sodium falls below 142 mEq/L
cells swell
How will a brain cell composite for hypernatremia (dehydration)
regulatory volume increase (RVI) via INCREASE of electrolytes
What does the term “third space” mean when referring to body fluid compartment?
a space that doesn’t equilibrate with extracellular fluid and usually results in loss of blood volume
Does edema only afflict extracellular compartments?
NO
What key factors drives intracellular edema during ischemia (Lack of blood flow)?
failure of ionic pumps that leads to accumulation of intracellular sodium
What are the 3 factors that describe endogenous prevention of extracellular edema?
1) low compliance in interstitium
2) wide range of lymph flow
3) washdown of interstitial fluid protein concentration
What controls the flow of blood entering a capillary?
precapillary sphincter
Which valve is considered a semilunar valve and is on the right side of the heart?
pulmonary
What part of the conduction system in the heart is predominately innervated with parasympathetic fibers from the left vagi?
AV node
A dog heart has a HW (heart weight)/BW (body weight of 3%. How would you describe this heart?
enlarged (should be 0.6%)
In a 2 or 3 chambered heart, what typically lies between the ventricle and aorta?
conus/bulbus arteriosus
What are the 3 main aspects of single-unit smooth muscle?
1) controlled as a unit
2) found throughout blood vessels
3) has gap junctions