Prototype Drug Unit 5 & 7- Tetracylcine

Question 1

Therapeutic classification

Answer 1

Antibacterial

Question 2

Pharmacologic classification

Answer 2

Bacterial protein synthesis inhibitor, tetracycline

Question 3

Therapeutic effects and uses

Answer 3

Used for the treatment and prophylaxis of gram-positive and gram-negative bacteria. Used to kill H. Pylori.

Question 4

Mechanism of action

Answer 4

The growing amino acid chain of the bacterial is prematurely terminated and protein synthesis is inhibited.

Question 5

Adverse effects

Answer 5

Can affect vaginal, oral, and intestinal flora and cause super infections. Nausea, vomiting, epigastric burning, diarrhea, discoloration of teeth and photosensitivity.

Question 6

Contraindications

Answer 6

Allergic to it, not be used during pregnancy, be careful with patients who have hepatic or renal impairment.

Question 7

Drug interactions

Answer 7

Oral supplements, laxatives, or antacids that contain calcium, iron, magnesium, or aluminum. Decreases the effectiveness of oral contraceptives.