149 - Gas gangrene and other Clostridial Infections

Question 1

Clostridium is G(_), obligatory __.

Answer 1

+

anaerobic

Question 2

Clostridium can cause infections in the __, __, __. Other damage could be __ and __

Answer 2

GI
myonecrosis (deep tissues)
skin
bacteremia
TTS

Question 3

Clostridium produce 2 virulent toxins:
alpha- __ and blood __
theta- __ and __ activation

Answer 3

gas gangrene
stasis
lysis
phagocyte

Question 4

Gas in the biliary system can cause- ___ in diabetic patients.

Answer 4

emphysematous cholecystitis

Question 5

Skin infection can lead to -__ and __ (mainly __)

Answer 5

necrotizing fasciitis
Fournier’s gangrene
C. perfringens

Question 6

Treating polymicrobial CD is done according to sensitivity: __ + __/__. If further treatment is needed, replace __ with __/__ or add __/__

Answer 6

ampicillin + clindamycin/metronidazole
ampicillin
piperacillin/carbapenem
fluoroquinolone/aminoglycoside

Question 7

Food poising occur - h post digestion. Causes severe __ and __ pain

Answer 7

7-30
diarrhea
epigastric

Question 8

Which strain causes clostridial bacteremia?

Answer 8

C. septicum

Question 9

C. septicum is more common in __/__/__

Answer 9

chronic
oncologic (colon)
immunocompromised

Question 10

C. septicum can create __ in the __/__/__. It can also form lung __

Answer 10

abscess
brain
abdomen
conjunctiva 
empyema

Question 11

C. septicum should be treated quickly with __ +__

Answer 11

penicillin

clindamycin