199 - Enterovirus, Parechovirus, and Reovirus Infections

Question 1

Enterovirus __ in the GI system but do not normally cause __.

Answer 1

multiply

gastroenteritis

Question 2

Enterovirus are sensitive to __ disinfection but not __ or __.

Answer 2

chlorine
soap
alcohol

Question 3

Common enteroviruses relevant to human are: 3

Answer 3

coxsackievirus
poliovirus
echovirus

Question 4

Poliovirus transmission is by __

Answer 4

ingestion

Question 5

After infection, poliovirus reaches the GI __- mostly the __ patches. From there it moves to regional __, and then to the __- first viremia.

Answer 5

mucosa
Peyer’s
LN
blood

Question 6

Eventually it reaches the posterior __ cells.

Answer 6

horn

Question 7

Incubation period of poliovirus is __.

Answer 7

2-14 days

Question 8

Young children __ develop significant disease when exposed to poliovirus, unlike older children/adults which may develop __.

Answer 8

do not

paralysis

Question 9

What are the 5 possible presentations of poliovirus?

Answer 9

abortive poliomyelitis 
non paralytic poliomyelitis 
paralytic poliomyelitis
vaccine associated poliomyelitis
post polio syndrome

Question 10

Abortive poliomyelitis characteristics include: 5. The symptoms usually pass after 3 days

Answer 10

fever
lethargy+ myalgia
sore throat
headache

Question 11

Non paralytic poliomyelitis- aseptic __. CSF will show __, normal __, and normal/slightly elevated __.

Answer 11

meningitis
lymphocytic pleocytosis
glucose
protein

Question 12

Paralytic poliomyelitis is more common in: 3

Answer 12

adults
pregnancy
physical exertion

Question 13

Paralytic poliomyelitis starts with __ meningitis-> strong __/__ pain->__.

Answer 13

aseptic
back/neck
weakness

Question 14

Children may experience - paralytic poliomyelitis.

Answer 14

bi-phasic

Question 15

Paralytic poliomyelitis weakness tens to involve mostly the __ and is usually __. The paralysis usually does not continue after the __ is relieved.

Answer 15

legs
asymmetric
fever

Question 16

Which patients are in increased risk for vaccine associated poliomyelitis?

Answer 16

hypo/agammaglobulinemia

Question 17

In children, enterovirus are the most common cause for __ __ and unspecific __.

Answer 17

aseptic meningitis

fever

Question 18

Generalized disease of the new born are the most severe enterovirus infections, happen at the 1st week of life. lab results may show: 4

Answer 18

leukocytosis
thrombocytopenia
increased liver functions
pleocytosis in CSF

Question 19

Generalized disease of the new born symptoms may include: 5

Answer 19

myocarditis
hypotension
fulminant hepatitis
DIC
meningitis / meningoencephalitis

Question 20

Pleurodynia= __

Answer 20

Bornholm disease

Question 21

Pleurodynia is characterized by: 2

Answer 21

fever

stinging pleuritic spasm/stinging abdominal pain

Question 22

What is the common pathogen causing pleurodynia?

Answer 22

coxsackievirus

Question 23

coxsackievirus is one of the most common pathogen causing __ and __ in children/newborn.

Answer 23

myocarditis

pericarditis