212 - Aspergillosis Flashcards
Immunocompetent patients with intensive exposure to 3, are in risk for aspergillosis infection.
construction
barn
compost
Incubation period is variable- between - days.
2-90
The main risk factor for aspergillosis infection is __.
immunosuppression
Examples for immunosuppression etiologies: 4
high dose steroids
CGD (neutrophils/phagocytes dysfunction)
advanced HIV
leukemia
Less prominent aspergillosis risk factors include: 4
pneumonia history
COPD
severe liver disease
iatrogenic immunomodulators (infliximab, ibrutinib)
What are the 3 risk factors for chronic aspergillosis?
COPD
TB
Hx pneumothorax
What are the 3 risk factors for allergic aspergillosis?
asthma
CF
bronchiectasis
Invasive pulmonary aspergillosis presentation include: 5
asymptomatic fever cough (hemoptysis/productive) chest discomfort dyspnea
Invasive pulmonary aspergillosis diagnosis is done only when there is a high suspicion. It is made by finding __ in the blood and __ showing __ sign.
antigen
CCT
halo
Invasive sinusitis aspergillosis is more common in __ and ___ patients.
leukemia
post BM transplantation
Tracheobronchitis aspergillosis is more common in __
post lung transplantation
Bronchitis aspergillosis is more common in patients with __ or __.
CF
bronchiectasis
Disseminated aspergillosis syndrome is more common in patients with severe __. It spreads fast, causing low __ and light __ before dramatic deterioration and death.
immunosuppression
fever
sepsis
What is the best diagnostic tool for brain aspergillosis?
MRI
Chronic pulmonary aspergillosis can be seen in __ and mistaken for lung __.
PET-CT
cancer
