164 - Brucellosis Flashcards
Brucella has several strains, each reservoir in a different animal: B. melitensis- \_\_ B. suis- \_\_ B. abortus- \_\_ B. canis- \_\_
sheep/goats/camels
swine
cattle/buffalo
canis
Brucellosis should be suspected in every patient with prolonged __ and __ difficulties. Ask also for __ ingestion, relatives with similar symptoms
fever
walking
unpasteurized dairy
Brucella incubation is between -
weeks-months
What is the typical fever pattern of brucellosis?
higher during the daylight
Which musculoskeletal symptoms are possible (appear in 50% of patients)? 5
monoarthritis
osteomyelitis/septic arthritis
spinal involvement
* children- more monoarthritis, adults- more fever and lumber pain
What is the DDx when suspecting brucelosis?
TB
CMV
typhoid fever
maleria
Name the more general symptoms of brucellosis: 5
B-symptoms lethargy flu symptoms (myalgia/headache/chills) hepatosplenomegaly lymphadenopathy
Which organs tend to get involved in brucellosis?
epididymis-orchitis uterus (abortion) lung (dry cough) neurological (depression/lethargy/meningoencephalitis) IE (aortic valve)
What are the typical lab results for brucellosis?
elevated liver enzymes
lymphocytosis
anemia
elevated inflammation markers
The coagulation functions of brucellosis may show __ or __
thrombocytopenia
DIC
When examining the CSF/synovial fluid of patients with brucellosis we might see __ and decreased __. Notice __ might be elevated
lymphocytosis
glucose
ADA (Adenosine deaminase)
When performing LN/liver biopsy for a brucellosis patient look for non __ __
necrotizing
granuloma
Where can you culture brucella from? 4
blood
CSF
synovial fluid
BM
Brucella culture is successful in -%, grows within _ days, but wait at least _ weeks.
50-70
10
6
__ and __ are also useful in brucella diagnosis
serology
PCR
