207 - Histoplasmosis

Question 1

In immunocompetent patient, __ are formed around the infected areas.

Answer 1

granulomas

Question 2

In immunocompromised patient __ occurs.

Answer 2

PDH-progressive disseminated histoplasmosis

Question 3

PDH may involve different organs such as: 5

Answer 3

BM
spleen
liver
adrenal
mucocutaneous membrane

Question 4

Histoplasma transmission is usually via ___ inhalation.

Answer 4

microconidia

Question 5

Symptoms appear - weeks post exposure, and include __-like signs.

Answer 5

1-4

flu

Question 6

In the acute phase- imaging may show __ signs: 2

Answer 6

pneumonitis
mediastinum adenopathy
pulmonary infiltration

Question 7

Rheumatic signs may also appear such as __ or __.

Answer 7

arthritis
arthralgia
erythema nodosum

Question 8

Infected LN may undergo __ and create __ between different organs, large blood vessels, esophagus.

Answer 8

necrosis

fistula

Question 9

Cavitary histoplasmosis can be seen in ___.

Answer 9

smokers

Question 10

Cavitary histoplasmosis include: 5

Answer 10

productive cough
dyspnea
low grade fever
night sweating
weigh loss

Question 11

Imaging of cavitary histoplasmosis will show infiltration of the __, together with __ and __ thickening.

Answer 11

upper lobes
cavitation
pleural

Question 12

Mediastinum __ is a __ post disease complication. It causes __.

Answer 12

fibrosis
fatal
SVCS

Question 13

Diagnosis is made with __, __, __ (in immunocompetent)

Answer 13

culture
antigens
serology

Question 14

Treatment- __ or in severe cases- __

Answer 14

AmB

Itraconazole