Demyeliniserende sykdommer, men ikke MS Flashcards

1
Q

Tre grupper demyeliniserende sykdommer

A

MS !! De fleste…
NMO-SD
MOG-AD

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2
Q

AQP4

A

aquaporin-4

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3
Q

AQP4-IgG positiv NMO-SD

A

AQP4-ON
AQP4-myelitt
AQP4-cerebral

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4
Q

AQP4-ON

A

OptikusNevritt

Affeksjon av bakre deler av chiasma/synsnerve

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5
Q

AQP4-myelitt

A

Sentrale langstrakte lesjoner i medulla, oftest => 3

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6
Q

AQP4-IgG positiv NMO-SD

A

AQP4-CSF: høyt celletall, høyt protein, <20% OCB
Atakkbehandling: ivMP, tillegg plasmaferese, (IVIG), steroidhale
Forebyggende beh: Rituximab (1.valg!!), Imurel, Cellcept

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7
Q

NMO-atakk

A

Et enkelt atakk kan gjøre pasienten __ og __!

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8
Q

Et enkelt NMO-atakk kan gjøre pasienten…

A

… blind og paraplegisk. Atakkbeh viktig!!

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9
Q

MOG-IgG positiv EM

A

MOG-ON
MOG-myelitt
MOG-cerebral
MOG-CSF

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10
Q

MOG

A

MyelinOligodendrocytterGlykoprotein

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11
Q

Atakkbehandling MOG-IgG positiv EM

A
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