Musculo-Skeletal Diseases Flashcards Preview

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Flashcards in Musculo-Skeletal Diseases Deck (105)
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1
Q

Diseased where there is decreased in bone mass due to a change in serum calcium or phosphorus or Vitamin D anddecreased estrogen.

A

Osteoporosis

2
Q

This is the most common cause of fracture in patients older than 60 years old.

A

Osteoporosis

3
Q

Disease where there is increased in bone mass chracterized by a failure of osteoclast to resorb the bone

A

Osteopetrosis

4
Q

Radiographic appearance of Osteopetrosis

A

Ground-glass

5
Q

Disease that results in failure of new bone to mineralize.

A

Vitamin D deficiency

6
Q

Causes of vitamin D deficiency

A

Decreased dietary phosphate intake
Malabsorption of fats
Decreased sunlight exposure
Kidney failure

7
Q

Vitamin D deficiency in children

A

RICKETS

8
Q

Pathognomonic/ radiographic sign of rickets

A

Rachitic rosary or Pectus carinatum or pigeon chest

9
Q

Oral manifestation of rickets

A

Delayed in eruption and abdnormal dentin

10
Q

Vitamin deficiency in adult who are 50 years old and above

A

Osteomalacia

11
Q

Disease caused by defective formation of collagen I

A

Osteogenesis imperfecta

12
Q

Oral manifestation of Oesteogenesis imperfecta

A

Dentinogenesis imperfecta I

13
Q

Pathognomonic sign of osteogenesis imperfecta

A

Blue sclera

14
Q

Reason for a blue sclera in OI

A

Lack of collagen type I causing reflection of the back of the eye to appear

15
Q

Disease characterized by abnormal bone remodeling leading to distortion of bone architecture and cancer of the bone.

A

Paget’s disease

16
Q

Disease common to blindness and deafness and px complains of “I CAN’T WEAR MY HAT”

A

Paget’s disease

17
Q

Primary disease of Paget’s disease

A

Leontiassis ossea

18
Q

Laboratory finding in Paget’s disease

A

Increased serum alkaline phosphatase

19
Q

Increased serum acid phosphatase

A

prostate cancer

20
Q

Radiographic appearance of Paget’s disease

A

Cotton wool appearance

21
Q

Histologic appearance of Paget’s disease

A

Jigsaw-puzzle appearance

Mossaic pattern

22
Q

cancer of the bone

A

Osteosarcoma

23
Q

Systemic condition that requires annual relining of denture base

A

Paget’s disease

24
Q

Bone (head to toe) most commonly affected by Paget

A

Pelvis

Spine

25
Q

Bone in the head and neck most commonly affected by Paget’s

A

Maxilla

26
Q

Inflammation process of the entire bone, including the cortex and the periosteum recognizing that the pathological process is rarely confined to endosteum

A

Osteomyelitis

27
Q

Causative agent of osteomyelitis

A

S. aureus

28
Q

Best antibiotic highly concentrated in bone than in serum

A

Clindamycin

29
Q

Treatment for Osteomyelitis

A

Clindamycin

30
Q

Types of Osetomyelitis

A
Acute suppurative osteomyelitis
Chronic suppurative osteomyelitis
Chronic focal sclerosing osteomyelitis
Chronic diffuse sclerosing osteomyelitis
Garre's chronic non-suppurative sclerosing osteitis
31
Q

A serious sequela of periapical infection that results in diffuse spread of injection

A

Acute suppurative osteomyelitis

32
Q

Cause of Acute suppurative osteomyelitis

A

Dental infection

33
Q

Radiographic appearance of of Acute suppurative osteomyelitis

A

Moth-eaten

34
Q

Histologic finding of Acute suppurative osteomyelitis

A

Sequestra

35
Q

Tx of Acute suppurative osteomyelitis

A

Clindamycin

36
Q

If Acute suppurative osteomyelitis is left untreated

A

Chronic suppurative osteomyelitis

37
Q

Osteomyelitis occurs due to unusual reaction of bone to infection

A

Chronic focal sclerosing osteomyelitis

38
Q

Other name of Chronic focal sclerosing osteomyelitis

A

Condensing osteitis

39
Q

In contrast to focal type, this disease may occur at any age group and no gender predilection

A

Chronic diffuse sclerosing osteomyelitis

40
Q

Radiographic appearance of Chronic diffuse sclerosing osteomyelitis

A

Cotton wool

41
Q

There is a focal gross thickening of the periosteum with peripheral reactive bone formation resulting from mild reaction or infection

A

Garre’s chronic non-suppurative sclerosing osteitis

42
Q

Formation of new bone

A

Involucrum

43
Q

Radiographic appearnce of Garre’s chronic non-suppurative sclerosing osteitis

A

Onion peel

44
Q

A rare form of osteomyelitis

A

Brodie’s abscess

45
Q

It involves subacute or chronic infection of the bone with development of a localized abscess within the metaphysis of long bones

A

Brodie’s abscess

46
Q

Brodie’s abscess is found in?

A

Osteomyelitis

47
Q

It is caused by replacement of normal bone with an irregular bone containing fibrous connective tissue

A

Fibrous dysplasia

48
Q

Bone with fibrous dysplasia is (brittle, elastic)

A

Elastic

49
Q

Radiographic appearance of fibrous dysplasia

A

ground glass

50
Q

Pathognomonic sign of fibrous dysplasia

A

hockey-stick deformity

51
Q

Other diseases with ground glass appearance

A

Hyperparathyroidism
Osteopetrosis
fibrous dysplasia

52
Q

Bone commonly affected with fibrous dysplasia

A

Tibia

53
Q

Histologic feature if fibrous dysplasia

A

Chinese-character

54
Q

What 2 diseases of bone predispose to osteosarcoma

A

Paget’s disease

Fibrous dysplasia

55
Q

Most common fibrous dysplasia that affects one bone

A

Monostotic

56
Q

Type of fibrous dysplasia that affects multiple bone

A

Polyostotic

57
Q

2 types of polyostotic fibrous dysplasia

A

McCune-Albright syndrome

Jaffe-Lichenstein syndrome

58
Q

Fibrous dysplasia affecting multiple bones with endocrine disorders

A

McCune-Albright syndrome

59
Q

Polyostotic fibrous dysplasia that affects multiple bones only

A

Jaffe-Lichenstein syndrome

60
Q

Pathognomonic sign of McCune-Albright syndrome

A

Cafe-au-lait spots

61
Q

Cafe-au-lait in the iris

A

Lisch spot

62
Q

Cae-au-lait in the axilla

A

Crows’s sign

63
Q

diameter of cafe-au-lait spots

A

> 1.6 cm in diameter

64
Q

Group of diseases that are caused by the proliferation of langerhan’s cell

A

Langerhancell granulomatosis

65
Q

Other name for Langerhancell granulomatosis

A

Histiocytosis X

66
Q

Type of histiocytosis X defined as an acute disseminated form that is fatal in infants.

A

Letterer-siwe disease

67
Q

Signs and symptoms of Langerhancell granulomatosis

A
Rash
Fever
Hemorrhage
Splenomegaly
Lymphadenopathy
68
Q

Type of histiocytosis X defined as a chronic,disseminated form.

A

Hand-schuller-christian disease

69
Q

Triad of Hand-schuller-christian disease

A

Bone lesion
Exophthalmos
Diabetes insipidus

70
Q

Histologic finding of Hand-schuller-christian disease

A

Birebeck granules

71
Q

Radiographic appearance of Hand-schuller-christian disease

A

Multiple punched out

72
Q

Type of histiocytosis X that is localized and is the least severe form.

A

Eosinophilic granuloma

73
Q

Oral manifestation of eosinophilic granuloma

A

Tooth mobility

periodontitis

74
Q

Swelling of lymphnodes with pain

A

Lymphadenopathy

75
Q

The most common true primary bone tumor

A

Osteosarcoma

76
Q

Radiographic appearance of oseteosarcoma

A

Codman’s triangle

Sun-burst

77
Q

Histologic finding of osteosarcoma

A

Touton giant cells

78
Q

Treatment of osteosarcoma

A

Amputation

79
Q

Osteosarcoma metastasize in?

A

Lungs

80
Q

Osteosarcoma affects what true primary bone?

A

Long bones

81
Q

Most common bone affected with osteosarcoma

A

Femur

82
Q

True/False. Osteosarcoma does not recur

A

False

83
Q

The most common cancer of the bone in children

A

Metastatic carcinoma

84
Q

Most common carcinoma in oral cavity

A

SCC

85
Q

Number one metastatic site of carcinoma

A

Bone

86
Q

Most common site of carcinoma in the head and neck

A

Angle of mandible

87
Q

Cancer that affects long bones, cartilage, and nerves

A

Ewing’s sarcoma

88
Q

Other name of ewing’s sarcoma

A

Round cell myeloma

89
Q

Radiographic appearnceof Ewing’s sarcoma

A

Onion skin

Moth-eaten

90
Q

Other diseases with moth-eaten appearance

A

Burkitt’s lymphoma

Osteomyelitis

91
Q

Disease caused by delayed or abnormal growth of cartilage.

A

Achrondroplasia

92
Q

Oral manifestation of achondroplasia

A

Mandibular prognathism or Class III

93
Q

Small maxilla in achondroplasia is due to?

A

Deficiency of maxilla due to underdeveloped nasal cartilage

94
Q

Second most common primary bone tumor

A

Chondrosarcoma

95
Q

Radiographic appearance of Chondrosarcoma

A

Popcorn-calcification

96
Q

An autoimmune that causes inflammation of the synnovial membrane

A

Rheumatoid arthritis

97
Q

The earliest sign of R.A. is

A

PANNUS formation

98
Q

What is Pannus?

A

Inflammed bursa

99
Q

Most common form of arthritis

A

Osteoarthritis

100
Q

Diseae where there is a formation of bony spurs(osteophyte) at the margins.

A

Osteoarthritis

101
Q

Oher name for asteoarthritis

A

Wear and Tear

102
Q

Osteoarthritis that affects the proximal joint

A

Bouchard osteophyte

103
Q

Osteoarthritis that affects the distal joint

A

Heberden osteophyte

104
Q

An autoimmune disease caused by autoantibodies to acetylcholine receptors

A

Myasthenia gravis

105
Q

Treatment of myasthenia gravis

A

Neostigmine

Pyridostigmine