Flashcards in Week 4 sER Module Deck (7)
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1
what is the structural difference between sER and rER
smooth ER lacks attached ribosomes.
2
what is the role of sER?3
1. synthesize lipids (FAs, phsopholipids, steroid hormones)
2. store calcium
3. contains detoxifying enzymes
3
what is the role of the sER in the cells of the adrenal cortex?
produce steroid hormones
4
what is the role of sER in skeletal muscle cells?
sER is called the sarcoplasmic reticulum. sER sequesters the calcium needed for muscle contraction. Calcium released in response to T-tubule signaling (depolarization)
5
what is the role of sER in hepatocytes?
sER contains a variety of detoxifying enzymes anchored in the sER membrane (Cytochrome P450)
6
what alterations/modifications does the detoxifying enzymes of liver cells make?
make hydrophobic compounds hydrophilic so they can be excreted.
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