Week 5 necrosis Flashcards Preview

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Flashcards in Week 5 necrosis Deck (8)
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1
Q

contrast karyolysis, pyknosis, and karyorrhexis

A

karyolysis: nucleus dissolves
pyknosis: nucelus condenses
karyorrhexis: nucleus fragments

2
Q

what are the cytoplasmic changes associated with necrosis?

A

cytoplasmic coagulation related to Ca influx(necrotic cells stain darker)

3
Q

what type of necrosis is described as “tomb stones” cells that maintain shape, with contraction bands, an abundance of neutrophils, and often seen in ischemia?

A

coagulative necrosis. do you know what this looks like on a slide? (heart, kidney)

4
Q

what type of necrosis is often seen in abscessed tissue and is decribed as being filled with cell debris, have aggregates of bacteria?

A

liquefactive necrosis (brain, abscess)

5
Q

what type of necrosis is described as looking like cottage cheese and has round “cookie-like” granulomas when stained?

A

caseous necrosis (lungs)

6
Q

what type of necrosis is described as soap bubbles with yellowing tissue due to calcium deposits?

A

fat necrosis (pancreas, breast)

7
Q

which necrosis types are associated with accute inflammation? chronic?

A

acute: coagulative, liquefactive
chronic: caseous, fat

8
Q

during the inflammatory response, which cells arrive first? which cells are there after prolonged necrosis?

A

first: neutrophils
prolonged: macrophages

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